Date published: 2025-9-6

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CAMK2A/CaMKII alpha 抗体 (A-1): sc-13141

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说明书
  • CAMK2A/CaMKII alpha 抗体 A-1 是小鼠单克隆 IgG2a κ,CAMK2A/CaMKII alpha抗体, 在73篇文献中引用,规格为200 µg/ml
  • 免疫mouse物种的CaMKIIα的氨基酸303-478
  • CAMK2A/CaMKII alpha 抗体 (A-1) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 CaMKIIα
  • 抗CAMK2A/CaMKII alpha抗体(A-1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取CAMK2A/CaMKII alpha (A-1): sc-13141免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP 是 CAMK2A/CaMKII alpha 抗体 (A-1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与CAMK2A/CaMKII alpha 抗体 (A-1) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

CaMKIIα抗体(A-1)是一种小鼠单克隆IgG2a kappa轻链抗体,可通过应用如蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、免疫组织化学和酶联免疫吸附测定(ELISA)在小鼠、大鼠和人类样本中检测CaMKIIα。CaMKIIα (A-1) 抗体有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 结合物。CaMKIIα在细胞信号传导通路中发挥着关键作用,特别是在神经元突触可塑性和记忆形成调节中,因此CaMKIIα对于认知功能至关重要。CaMKIIα主要位于细胞质中,也存在于细胞核中,CaMKIIα可在细胞核中影响基因表达和细胞对钙信号的反应。CaMKIIα在激活后转移到细胞核中,这凸显了CaMKIIα在神经元功能和可塑性长期变化中的重要作用。此外,CaMKIIα还会经历多种翻译后修饰,包括磷酸化,从而调节CaMKIIα的活性及其与其他蛋白的相互作用,进一步强调了CaMKIIα在复杂信号网络中的作用。CaMKIIα(A-1)单克隆抗体使研究人员能够深入了解钙依赖性信号传导的机制及其在神经生物学和其他生理过程中的意义。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CAMK2A/CaMKII alpha 抗体 (A-1) 参考文献:

  1. 心脏肌浆网磷酰班激酶是一种独特的 delta-CaM 激酶同工酶。  |  Baltas, LG., et al. 1995. FEBS Lett. 373: 71-5. PMID: 7589437
  2. 钙离子/钙调蛋白依赖性蛋白激酶级联的特征。钙/钙调蛋白依赖性蛋白激酶激酶的分子克隆和表达。  |  Tokumitsu, H., et al. 1995. J Biol Chem. 270: 19320-4. PMID: 7642608
  3. 钙/钙调蛋白依赖性蛋白激酶II能下调人类T细胞中钙调素和蛋白激酶C介导的细胞因子基因转录途径。  |  Hama, N., et al. 1995. J Exp Med. 181: 1217-22. PMID: 7869038
  4. KN-93 是 CaMK-II(多功能 Ca2+/CaM 激酶)的一种阻抑剂,可诱导 NIH 3T3 细胞的 G1 细胞周期停滞和细胞凋亡。  |  Tombes, RM., et al. 1995. Cell Growth Differ. 6: 1063-70. PMID: 8519682
  5. 过表达 Ca2+/calmodulin 依赖性蛋白激酶 II 可抑制 PC12 细胞的神经元生长。  |  Tashima, K., et al. 1996. J Neurochem. 66: 57-64. PMID: 8522989
  6. Jurkat T 淋巴细胞中 CaM 激酶对 Ca2+/calmodulin 依赖性蛋白激酶(CaM-激酶)IV 的激活。  |  Park, IK. and Soderling, TR. 1995. J Biol Chem. 270: 30464-9. PMID: 8530476

订购信息

产品名称产品编号规格价格数量收藏夹

CAMK2A/CaMKII alpha 抗体 (A-1)

sc-13141
200 µg/ml
RMB2377.00

CAMK2A/CaMKII alpha (A-1): m-IgG Fc BP-HRP 套装

sc-528268
200 µg Ab; 10 µg BP
RMB2662.00

CAMK2A/CaMKII alpha (A-1): m-IgGκ BP-HRP 套装

sc-520605
200 µg Ab, 40 µg BP
RMB2662.00

CAMK2A/CaMKII alpha 抗体 (A-1) AC

sc-13141 AC
500 µg/ml, 25% agarose
RMB3129.00

CAMK2A/CaMKII alpha 抗体 (A-1) HRP

sc-13141 HRP
200 µg/ml
RMB2377.00

CAMK2A/CaMKII alpha 抗体 (A-1) FITC

sc-13141 FITC
200 µg/ml
RMB2482.00

CAMK2A/CaMKII alpha 抗体 (A-1) PE

sc-13141 PE
200 µg/ml
RMB2580.00

CAMK2A/CaMKII alpha 抗体 (A-1) Alexa Fluor® 488

sc-13141 AF488
200 µg/ml
RMB2685.00

CAMK2A/CaMKII alpha 抗体 (A-1) Alexa Fluor® 546

sc-13141 AF546
200 µg/ml
RMB2685.00

CAMK2A/CaMKII alpha 抗体 (A-1) Alexa Fluor® 594

sc-13141 AF594
200 µg/ml
RMB2685.00

CAMK2A/CaMKII alpha 抗体 (A-1) Alexa Fluor® 647

sc-13141 AF647
200 µg/ml
RMB2685.00

CAMK2A/CaMKII alpha 抗体 (A-1) Alexa Fluor® 680

sc-13141 AF680
200 µg/ml
RMB2685.00

CAMK2A/CaMKII alpha 抗体 (A-1) Alexa Fluor® 790

sc-13141 AF790
200 µg/ml
RMB2685.00

如何获得该产品小样

Asked by: xiongY
感谢您的提问。关于此问题的详细细节,欢迎通过:电话(+86) 021-60936350、邮箱[email protected]、或选择网页上Live Chat中的“中文支持”,联系我们的技术支持部门。 Thank you for your inquiry. For more detailed information about this question, please contact our Asian Technical Service team at (+86) 021-60936350 or [email protected] or by live chat on our website.
Answered by: Technical Support 15
Date published: 2018-05-14

Which is the best among your CaMKII alpha antibodies for immunofluorescence on PFA perfused mouse brain frozen sections?

Asked by: MaPo61
Thank you for your question. I would recommend sc-13141, CaMKIIα Antibody (A-1). https://www.scbt.com/scbt/product/camkiialpha-antibody-a-1 Please contact us if you have any further questions. You can reach us at 800-457-3801 ext 2, or by chat directly on our website, www.scbt.com.
Answered by: Tech Service
Date published: 2018-01-31

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: AbPolly
Thank you for your question. We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety Please contact Technical Service if you have further questions concerning this product.
Answered by: Technical Support 6
Date published: 2017-01-09
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Rated 4 out of 5 by from Anti-CAM2KA worked well in IHCAnti-CAM2KA antibody worked well in IHC using human tissue samples
Date published: 2025-06-06
Rated 4 out of 5 by from Good antibody for immunostainingTested the anti-CamK2a antibody in immunofluorescence staining on mouse hippocampal neurons in culture at 16 DIV. Antibody works fine at 1:100 dilution.
Date published: 2024-12-02
Rated 4 out of 5 by from FACS stainingWe detected it in HEK293T cells by intracellular FACS staining.
Date published: 2024-06-25
Rated 5 out of 5 by from Good! Works well for western blotI tried 1:500 dilution for western blot and it showed a strong and clear band with low background.
Date published: 2022-02-10
Rated 4 out of 5 by from GoodA band of predicted size was detected in WB (mouse brain lysate).
Date published: 2020-06-26
Rated 5 out of 5 by from works for western blotTried for western blot at 1:200 dilution. The band was very strong. Will dilute more for future samples.
Date published: 2020-06-05
Rated 5 out of 5 by from CaMKIIα AntibodyThis antibody worked very well in our Western blotting experiments.
Date published: 2019-01-09
Rated 5 out of 5 by from 功能很出色!我一个月前用了此产品,并为此感到高兴。产品的染色效果很好,期待再次使用。希望在再次购买前获得小样使用。
Date published: 2018-04-18
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CAMK2A/CaMKII alpha 抗体 (A-1) is rated 4.5 out of 5 by 16.
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