Date published: 2025-9-8

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CA IV 抗体 (G-11): sc-74527

5.0(2)
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说明书
  • CA IV抗体(G-11)是小鼠单克隆IgG2b κ, 在2篇文献中引用,规格为200 µg/ml
  • 免疫mouse物种的CA IV的氨基酸1-50
  • 推荐用于 mouse, rat 和 human 来源的CA IV WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP是CA IV Antibody (G-11) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与CA IV Antibody (G-11) 搭配使用(请参阅下面的订购信息)。

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関連項目

碳酸酐酶IV(CA IV)通过糖基磷脂酰肌醇锚定在细胞膜的外表面,在那里它催化CO2/HCO3(-)的水合-脱水反应。CA IV存在于微毛细血管的血浆面以及人眼的脉络膜毛细血管中。CA IV促进肾脏的酸化,并负责调节大脑中间质pH(pHo)的瞬变。靶向受损会导致HCO3-分泌中断,并与囊性纤维化细胞的功能障碍有关。碳酸酐酶是催化二氧化碳可逆水合的锌金属酶。它们参与呼吸、钙化、酸碱平衡、骨吸收以及房水、脑脊液、唾液和胃酸的形成。碳酸酐酶在组织分布和亚细胞定位方面表现出广泛的多样性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CA IV 抗体 (G-11) 参考文献:

  1. 小鼠胎盘中的碳酸酐酶IV表达。  |  Rosen, O., et al. 2001. Am J Physiol Regul Integr Comp Physiol. 280: R365-75. PMID: 11208563
  2. 碳酸酐酶IV和XIV基因敲除小鼠:各自碳酸酐酶在缓冲脑细胞外空间中的作用。  |  Shah, GN., et al. 2005. Proc Natl Acad Sci U S A. 102: 16771-6. PMID: 16260723
  3. 大鼠星形胶质细胞表面碳酸酐酶IV活性的功能演示。  |  Svichar, N., et al. 2006. Glia. 53: 241-7. PMID: 16265666
  4. 碳酸酐酶IV在碳酸氢盐介导的小鼠和人类精子活化中的作用。  |  Wandernoth, PM., et al. 2010. PLoS One. 5: e15061. PMID: 21124840
  5. 在注射了cRNA的卵母细胞和小鼠神经元中,GPI锚定的碳酸酐酶IV表现出胞内和胞外活性。  |  Schneider, HP., et al. 2013. Proc Natl Acad Sci U S A. 110: 1494-9. PMID: 23297198
  6. 膜锚碳酸酐酶 IV 通过其伴侣蛋白 CD147 和 GP70 与单羧酸盐转运体相互作用。  |  Forero-Quintero, LS., et al. 2019. J Biol Chem. 294: 593-607. PMID: 30446621
  7. 碳酸酐酶 IV 通过调节细胞周期抑制胃癌细胞增殖。  |  Wang, B., et al. 2020. Oncol Lett. 20: 4. PMID: 32774478
  8. 碳酸酐酶IV缺乏导致小鼠宫内胚胎丢失。  |  Schumann, S., et al. 2025. Cells Tissues Organs. 1-11. PMID: 39908001
  9. 膜结合型碳酸酐酶同工酶(CA IV)在人类男性生殖道中的位置。  |  Parkkila, S., et al. 1993. J Histochem Cytochem. 41: 751-7. PMID: 8468457
  10. 大鼠和人类胃肠道区域、细胞和亚细胞定位中的碳酸酐酶IV表达。  |  Fleming, RE., et al. 1995. J Clin Invest. 96: 2907-13. PMID: 8675662

订购信息

产品名称产品编号规格价格数量收藏夹

CA IV 抗体 (G-11)

sc-74527
200 µg/ml
RMB2377.00

CA IV (G-11): m-IgG Fc BP-HRP 套装

sc-551971
200 µg Ab; 10 µg BP
RMB2662.00

Hi, is this antibody could be used for Flow cytometry? do you have any conjugated CA4 antibody for Flow?

Asked by: Cheng
This antibody has been validated for Flow Cytometry. The link below shows the conjugations that are offered for CA4. https://www.scbt.com/p/ca-iv-antibody-h-5
Answered by: Technical Service
Date published: 2023-10-31

I need to use an antibody to detect the protein in samples of equine origin. Do you know if sc-74527: CA IV (G-11) mouse monoclonal antibody will work?

Asked by: Dr Ninau Qelp
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
  • y_2025, m_9, d_7, h_4CST
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Rated 5 out of 5 by from Produced positive Western Blot data of CAProduced positive Western Blot data of CA IV expression in non-transfected and mouse CA IV transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-01-15
Rated 5 out of 5 by from Satisfactory Western Blot data of mouse recombinantSatisfactory Western Blot data of mouse recombinant CA IV fusion protein. -SCBT QC
Date published: 2013-08-29
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CA IV 抗体 (G-11) is rated 5.0 out of 5 by 2.
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