Date published: 2025-9-6
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C1QBP Antibody (74.5.2) - Western Blotting - Image 356343
C1QBP 抗体 (74. 5. 2): sc-23885. MCF7 (A), HeLa (B) 和 NIH/3T3 (C) 全细胞裂解液中 C1QBP 表达的 Western 印迹分析.
C1QBP 抗体 (74. 5. 2): sc-23885. MCF7 (A), HeLa (B) 和 NIH/3T3 (C) 全细胞裂解液中 C1QBP 表达的 Western 印迹分析.

C1QBP 抗体 (74.5.2): sc-23885

4.6(9)
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说明书
  • C1QBP 抗体 74.5.2 是小鼠单克隆 IgG1 κ，C1QBP抗体, 在9篇文献中引用，规格为200 µg/ml
  • 与成熟C1QBP（aa 74-282）对应的重组C1QBP
  • C1QBP 抗体 (74.5.2) 推荐用于 WB, IP, IF, IHC(P) 和 FCM，检测mouse, rat 和human 来源的 mature and truncated form of C1QBP
  • 抗C1QBP抗体（74.5.2）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取C1QBP (74.5.2): sc-23885的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 C1QBP 抗体 (74.5.2) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与C1QBP 抗体 (74.5.2) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

C1QBP抗体（74.5.2）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、石蜡包埋切片免疫组织化学（IHCP）和流式细胞术（FCM）检测小鼠、大鼠和人类来源的C1QBP蛋白。C1QBP抗体（74.5.2）有非结合型和多种结合型可供选择，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。C1QBP，也称为gC1q-R、p32或透明质酸结合蛋白1，通过与C1q分子的球状头结合，从而抑制C1激活并调节补体系统，在免疫反应中发挥着至关重要的作用。C1QBP主要位于细胞的细胞质和线粒体中，参与细胞凋亡和细胞信号传导等多种细胞过程。C1QBP在血管内皮细胞中的存在凸显了其在维持血管完整性和调节炎症反应中的重要性。此外，C1QBP是前mRNA剪接因子SF2/ASF的一个亚基，将C1QBP与基因表达调控联系起来。C1QBP具有多种功能，与补体、凝血和激肽系统相互作用，这凸显了C1QBP在先天性和适应性免疫中的重要性，使抗C1QBP抗体（74.5.2）成为研究人员研究免疫机制和相关病理的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

C1QBP 抗体 (74.5.2) 参考文献:

  1. 多配体结合蛋白 gC1qR 的亚细胞定位。  |  Dedio, J., et al. 1999. Immunopharmacology. 45: 1-5. PMID: 10614982
  2. 人类 gC1qR/p32 基因 C1qBP。基因组组织和启动子分析。  |  Tye, AJ., et al. 2001. J Biol Chem. 276: 17069-75. PMID: 11278463
  3. C1qRp 界定了具有造血和肝脏潜能的新人类干细胞群。  |  Danet, GH., et al. 2002. Proc Natl Acad Sci U S A. 99: 10441-5. PMID: 12140365
  4. 人类内皮细胞上的经典补体激活途径。  |  Yin, W., et al. 2007. Mol Immunol. 44: 2228-34. PMID: 17173972
  5. 克隆的人类剪接因子 SF2 的功能表达：与 RNA 结合蛋白, U1 70K 和果蝇剪接调节因子的同源性。  |  Krainer, AR., et al. 1991. Cell. 66: 383-94. PMID: 1830244
  6. 人成纤维细胞透明质酸结合蛋白的分子克隆证实了它与与剪接因子 SF2 共同纯化的 P-32 蛋白的同一性。透明质酸结合蛋白作为 P-32 蛋白，与剪接因子 SF2 共同纯化。  |  Deb, TB. and Datta, K. 1996. J Biol Chem. 271: 2206-12. PMID: 8567680
  7. 通过原位杂交将编码C1q球状结构域结合蛋白（gC1q-R）的C1QBP分配到人类第17号染色体p13.3带。  |  Guo, N., et al. 1997. Cytogenet Cell Genet. 77: 283-4. PMID: 9284938
  8. 多配体结合蛋白 gC1qR（假定的 C1q 受体）是一种线粒体蛋白。  |  Dedio, J., et al. 1998. J Immunol. 160: 3534-42. PMID: 9531316

订购信息

产品名称产品编号规格价格数量收藏夹

C1QBP 抗体 (74.5.2)

sc-23885
200 µg/ml
RMB2377.00

C1QBP (74.5.2): m-IgG Fc BP-HRP 套装

sc-528378
200 µg Ab; 10 µg BP
RMB2662.00

C1QBP (74.5.2): m-IgGκ BP-HRP 套装

sc-520741
200 µg Ab, 40 µg BP
RMB2662.00

C1QBP (74.5.2): m-IgG1 BP-HRP 套装

sc-542905
200 µg Ab; 20 µg BP
RMB2662.00

C1QBP 抗体 (74.5.2) AC

sc-23885 AC
500 µg/ml, 25% agarose
RMB3129.00

C1QBP 抗体 (74.5.2) HRP

sc-23885 HRP
200 µg/ml
RMB2377.00

C1QBP 抗体 (74.5.2) FITC

sc-23885 FITC
200 µg/ml
RMB2482.00

C1QBP 抗体 (74.5.2) PE

sc-23885 PE
200 µg/ml
RMB2580.00

C1QBP 抗体 (74.5.2) Alexa Fluor® 488

sc-23885 AF488
200 µg/ml
RMB2685.00

C1QBP 抗体 (74.5.2) Alexa Fluor® 546

sc-23885 AF546
200 µg/ml
RMB2685.00

C1QBP 抗体 (74.5.2) Alexa Fluor® 594

sc-23885 AF594
200 µg/ml
RMB2685.00

C1QBP 抗体 (74.5.2) Alexa Fluor® 647

sc-23885 AF647
200 µg/ml
RMB2685.00

C1QBP 抗体 (74.5.2) Alexa Fluor® 680

sc-23885 AF680
200 µg/ml
RMB2685.00

C1QBP 抗体 (74.5.2) Alexa Fluor® 790

sc-23885 AF790
200 µg/ml
RMB2685.00

What is the optimal concentration for flow testing? (Cat #:sc-23885; Batch #: B2120) Mary

Asked by: Mary C
Thank you for your question. We recommend 1 µg normal immunoglobulins per 1 million cells. Here is our recomended protocol:https://www.scbt.com/resources/protocols/flow-cytometry
Answered by: BlakeJ
Date published: 2022-09-07

Can C1QBP (74.5.2): sc-23885 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: cjMara
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, C1QBP (74.5.2): sc-23885 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Great antibody.This antibody is so nice and I got the incredible band.
Date published: 2017-08-23
Rated 5 out of 5 by from Good antibodyI have used this antibody for detection of ectopically expressed p32 by western blotting, it works very well.
Date published: 2017-07-20
Rated 5 out of 5 by from Excellent functionIt works really well, used at 1:100 dilution, almost no other non-specific fluorescence
Date published: 2017-06-01
Rated 4 out of 5 by from good antibody for blockingI used this antibody for inhibition and it worked very well.
Date published: 2016-11-18
Rated 4 out of 5 by from Strong bands seen in WB using HLStrong bands seen in WB using HL-60 and Hep G2 whole cell lysates. -SCBT QC
Date published: 2015-06-12
Rated 4 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB. -SCBT QC
Date published: 2015-03-28
Rated 5 out of 5 by from Produced great immunoperoxidase cytoplasmicProduced great immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human duodenum tissue. -SCBT QC
Date published: 2015-02-23
Rated 4 out of 5 by from Publishable data in IF human COSPublishable data in IF human COS-7, HeLa, HEK293, 293T, and T-REX -293 (Invitrogen) cells -SCBT Publication Review
Date published: 2015-02-16
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C1QBP 抗体 (74.5.2) is rated 4.6 out of 5 by 9.
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