Date published: 2025-9-10

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Blood Group Lewis b 抗体 (2-25LE): sc-51513

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说明书
  • Blood Group Lewis b 抗体 2-25LE 是小鼠单克隆 IgG1, 在5篇文献中引用,提供 100 µg/ml
  • 针对从human卵巢囊肿液中分离的粘蛋白
  • 推荐用于 human 来源的Lewis b blood group antigen WB, IF 和 IHC(P)检测
  • 关于如何获取Blood Group Lewis b (2-25LE): sc-51513免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成Blood Group Lewis b 抗体 (2-25LE)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

血型Lewis b抗体(2-25LE)是一种IgG1小鼠单克隆血型Lewis b抗体,可通过WB、IF和IHC(P)检测人类血型Lewis b血清抗原。血型Lewis b抗体(2-25LE)可以作为非偶联的抗血型Lewis b抗体形式使用。糖基转移酶,如糖基转移酶,可以介导糖的区域和立体选择性转移,这是细胞表面糖结构的必要条件,也是生物识别过程的重要界面。糖基转移酶催化糖接受分子上的糖醛酸的共价结合。细胞表面上形成的糖基和共价结合的糖基是确保表面轮廓满足生理作用的必要条件,这些生理作用依赖于粘附分子,如选择素。造血系统依赖糖基转移酶来赋予表面糖结构的表型,从而介导适当的细胞粘附分子招募和细胞转运。血型Lewis b是糖脂和糖蛋白上携带的糖基决定因子。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Blood Group Lewis b 抗体 (2-25LE) 参考文献:

  1. 翼状胬肉中 Sialyl Lewis 表位表达的改变。  |  Creuzot-Garcher, C., et al. 1999. Invest Ophthalmol Vis Sci. 40: 1631-6. PMID: 10393028
  2. 人α1, 3-岩藻糖基转移酶 4 (FUT4) 基因在骨髓癌和结肠腺癌细胞系中的表达和转录调控。  |  Taniguchi, A., et al. 2000. Biochem Biophys Res Commun. 273: 370-6. PMID: 10873613
  3. 在小鼠中性粒细胞中,P-选择素糖蛋白配体-1和E-选择素配体-1被岩藻糖基转移酶Fuc-TIV和Fuc-TVII不同程度地修饰。  |  Huang, MC., et al. 2000. J Biol Chem. 275: 31353-60. PMID: 10882744
  4. 人α(1,3)-岩藻糖基转移酶 IV(FUTIV)基因的表达在 U937 细胞系中受麋鹿-1 的调控。  |  Withers, DA. and Hakomori, SI. 2000. J Biol Chem. 275: 40588-93. PMID: 11006292
  5. TGF-beta 1通过p38丝裂原活化蛋白激酶依赖途径强力诱导活化的CD4+ T细胞中的α(1,3)-岩藻糖基转移酶VII。  |  Wagers, AJ. and Kansas, GS. 2000. J Immunol. 165: 5011-6. PMID: 11046029
  6. 胃癌前体的 Lewis 抗原改变  |  Torrado, J., et al. 1992. Gastroenterology. 102: 424-30. PMID: 1732113
  7. 人类结直肠上皮的单克隆抗体:分化和肿瘤特征的标志物。  |  Richman, PI. and Bodmer, WF. 1987. Int J Cancer. 39: 317-28. PMID: 2434440
  8. 粘蛋白的免疫化学特征。多肽(M1)和多糖(A 和 Leb)抗原。  |  Bara, J., et al. 1988. Biochem J. 254: 185-93. PMID: 2460087

订购信息

产品名称产品编号规格价格数量收藏夹

Blood Group Lewis b 抗体 (2-25LE)

sc-51513
100 µg/ml
RMB2377.00

Is 51513 Ab suitable for ELISA detection?

Asked by: YuriSan
Thank you for your question. This antibody is only recommended for detection of Lewis b blood group antigen of human origin by WB, IF and IHC(P).
Answered by: Tech Support Europe
Date published: 2021-02-24

Can sc-51513: Blood Group Lewis b (2-25LE) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Cweed
Thank you for your question. Yes, sc-51513: Blood Group Lewis b (2-25LE) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24

is this antibody currently available? Blood Group Lewis b Antibody (2-25LE)

Asked by: Lori M
Thank you for your question. Please contact our Customer Care Department for current information about product stock and availability. Please call us toll-free at (800) 457-3801 option 1, email [email protected], or use our live chat.
Answered by: Technical Support
Date published: 2017-02-03
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Rated 5 out of 5 by from Good choice for Immunoperoxidase stainingThis antibody has been used for Immunoperoxidase staining in published research. -SCBT QC
Date published: 2023-09-14
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Blood Group Lewis b 抗体 (2-25LE) is rated 4.5 out of 5 by 2.
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