Date published: 2025-9-8

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β-Amyloid 抗体 (D-11): sc-374527

5.0(3)
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说明书
  • β-Amyloid抗体(D-11)是小鼠单克隆IgG1 κ, 在13篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的β-Amyloid的C-terminus的氨基酸663-687之间
  • beta-Amyloid 抗体 (D-11) 推荐用于WB, IP, IF, IHC(P) 和 ELISA ,检测 mouse, rat, human 和 来源的4 kDa β-Amyloid and Amyloid A4; 也和以下物种反应,包括: 和 equine, canine, bovine, porcine and avian
  • 抗beta-Amyloid抗体(D-11)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取β-Amyloid (D-11): sc-374527免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP是β-Amyloid Antibody (D-11) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现与β-Amyloid Antibody (D-11) 搭配使用(请参阅下面的订购信息)。

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関連項目

β-淀粉样蛋白抗体(D-11)是一种IgG1 κ小鼠单克隆β-淀粉样蛋白抗体(也称为β-淀粉样蛋白抗体或APP片段淀粉样蛋白β 663-687抗体),可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人类来源的4 kDa β-淀粉样蛋白和淀粉样蛋白A4。β-淀粉样蛋白抗体(D-11)以非偶联的抗β-淀粉样蛋白抗体形式存在,同时也存在多种偶联形式的抗β-淀粉样蛋白抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。淀粉样蛋白前体(APP)的蛋白水解产生β-淀粉样蛋白和淀粉样蛋白A4蛋白,它们存在于人类血小板中。淀粉样蛋白沉积与II型糖尿病、唐氏综合症和各种神经系统疾病有关,包括阿尔茨海默病。淀粉样前体蛋白(APP)经历选择性剪接,产生几种异构体。APP的蛋白水解切割导致形成4 kDa的淀粉样β/A4淀粉样蛋白。这种蛋白质参与神经原纤维缠结和斑块的形成,这些斑块是阿尔茨海默病患者老年斑的特征。APLP1(淀粉样前体样蛋白1)和APLP2在结构上与APP相似。人类APLP2是一种膜结合的精子蛋白,含有与阿尔茨海默病患者脑斑块中发现的APP跨膜细胞质结构域高度同源的区域。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

β-Amyloid 抗体 (D-11)

sc-374527
200 µg/ml
RMB2377.00

β-Amyloid (D-11): m-IgG Fc BP-HRP 套装

sc-525975
200 µg Ab; 10 µg BP
RMB2662.00

β-Amyloid 抗体 (D-11) AC

sc-374527 AC
500 µg/ml, 25% agarose
RMB3129.00

β-Amyloid 抗体 (D-11) HRP

sc-374527 HRP
200 µg/ml
RMB2377.00

β-Amyloid 抗体 (D-11) FITC

sc-374527 FITC
200 µg/ml
RMB2482.00

β-Amyloid 抗体 (D-11) PE

sc-374527 PE
200 µg/ml
RMB2580.00

β-Amyloid 抗体 (D-11) Alexa Fluor® 488

sc-374527 AF488
200 µg/ml
RMB2685.00

β-Amyloid 抗体 (D-11) Alexa Fluor® 546

sc-374527 AF546
200 µg/ml
RMB2685.00

β-Amyloid 抗体 (D-11) Alexa Fluor® 594

sc-374527 AF594
200 µg/ml
RMB2685.00

β-Amyloid 抗体 (D-11) Alexa Fluor® 647

sc-374527 AF647
200 µg/ml
RMB2685.00

β-Amyloid 抗体 (D-11) Alexa Fluor® 680

sc-374527 AF680
200 µg/ml
RMB2685.00

β-Amyloid 抗体 (D-11) Alexa Fluor® 790

sc-374527 AF790
200 µg/ml
RMB2685.00

β-Amyloid (D-11) 中和勝肽

sc-374527 P
100 µg/0.5 ml
RMB511.00

Is this antibody suitable for immunoprecipitation of the full-length/native Amyloid Precursor Protein (APP, uniprot P05067)?

Asked by: Solrac
Thank you for your question. Anti-β-Amyloid Antibody (D-11): sc-374527 recognises its target protein based on an epitope mapping between amino acids 663-687 at the C-terminus of β-Amyloid of human origin. It will detect variants of β-Amyloid protein containing this sequence.
Answered by: Tech Support Europe
Date published: 2022-04-21

Could you recommend this antibody for IF of CHO 7PA2 cells? And if not, would you suggest another more appropriate Ab?

Asked by: Anonymous
Thank you for your question. It seem this protein has not been well characterized in hamster and, therefore, not recommended for use with this sample. If you have additional questions, please feel free to contact Technical Service by phone, email or chat.
Answered by: Santa Cruz TS
Date published: 2021-07-06

What application is the blocking peptide sc-374527 P appropriate for?

Asked by: Dr Ninau Qelp
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Look no furtherThis is an excellent antibody for western blot analysis. It is good for detecting the APP intact protein and the Abeta peptide.
Date published: 2021-01-14
Rated 5 out of 5 by from Great monoclonal antibodyNice and strong bands in various samples with low to no background. IHCP stain was robust and specific
Date published: 2017-02-02
Rated 5 out of 5 by from Produced nice Western blot data ofProduced nice Western blot data of -Amyloid expression in H4 and PC-3 whole cell lysates and human brain tissue extract . -SCBT QC
Date published: 2014-02-16
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β-Amyloid 抗体 (D-11) is rated 5.0 out of 5 by 3.
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