Date published: 2025-9-6

021-6093-6350

SCBT Portrait Logo
Seach Input

β-2-Microglobulin 抗体 (G-10): sc-46697

4.9(7)
寫評論提問

说明书
  • β-2-Microglobulin抗体(G-10)是小鼠单克隆IgG2a κ, 在4篇文献中引用,规格为200 µg/ml
  • 免疫1-119氨基酸,对应于human来源β-2-Microglobulin全长
  • 抗-beta-2-Microglobulin 抗体 (G-10) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 β-2-Microglobulin
  • 抗beta-2-Microglobulin抗体(G-10)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取β-2-Microglobulin (G-10): sc-46697免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRPm-IgGκ BP-HRP 是 β-2-Microglobulin 抗体 (G-10) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与β-2-Microglobulin 抗体 (G-10) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

関連項目

β-2-微球蛋白抗体(G-10)是一种小鼠单克隆IgG2a kappa轻链抗体,可通过应用诸如蛋白质印迹(WB)、免疫沉淀( 免疫沉淀(IP)、免疫荧光(IF)、免疫组织化学和酶联免疫吸附测定(ELISA)等方法检测小鼠、大鼠和人类样本中的β-2微球蛋白。β-2微球蛋白(G-10)抗体有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。β-2-微球蛋白作为主要组织相容性复合物(MHC)I类分子的组成部分,在免疫系统中发挥着至关重要的作用,而MHC I类分子对于在细胞表面呈现抗原至关重要。这种呈现对于CD8+细胞毒性T淋巴细胞识别感染或恶性细胞至关重要,从而促进有效的免疫反应。β-2-微球蛋白位于细胞表面,与MHC I类分子的重链以非共价键结合,有助于其稳定性和正确折叠。值得注意的是,缺少β-2-微球蛋白会导致成熟的CD4-8+ T细胞缺失,这凸显了β-2-微球蛋白在T细胞发育和功能中的重要性。人类β-2-微球蛋白基因位于15q21-q22.2染色体上,编码一种119个氨基酸的蛋白质,该基因的突变与恶性黑色素瘤表型的进展有关。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

β-2-Microglobulin 抗体 (G-10) 参考文献:

  1. HLA-B27/beta 2 微球蛋白转基因大鼠的结肠炎  |  Sartor, RB. 2000. Int Rev Immunol. 19: 39-50. PMID: 10723676
  2. 绒毛合胞滋养细胞中 beta 2-微球蛋白的定位  |  Leitner, K., et al. 2002. Histochem Cell Biol. 117: 187-93. PMID: 11935295
  3. 透析中的β-2-微球蛋白处理。  |  Klinke, B., et al. 1989. Contrib Nephrol. 74: 139-46. PMID: 2702131
  4. 血液滤过过程中的β2-微球蛋白动力学。  |  Floege, J., et al. 1988. Nephrol Dial Transplant. 3: 784-9. PMID: 3147420
  5. β-2-微球蛋白前淀粉样寡聚体的结构异质性  |  Marcinko, TM., et al. 2020. J Mol Biol. 432: 396-409. PMID: 31711963
  6. 评估多血症病例中的β-2微球蛋白、促红细胞生成素和吸烟情况。  |  Mahe, K., et al. 2021. Int J Hematol. 114: 222-227. PMID: 34021850
  7. β2微球蛋白二聚体的界面动力学和生长模式。  |  Oliveira, NFB., et al. 2023. J Chem Inf Model. 63: 4447-4457. PMID: 37132512
  8. 慢性肝病患者血清中的β2-微球蛋白  |  Nakamura, S., et al. 1981. Tohoku J Exp Med. 134: 221-2. PMID: 6171912
  9. α-干扰素对血清β-2-微球蛋白的影响  |  Remes, K., et al. 1996. Leuk Lymphoma. 21: 233-8. PMID: 8726404
  10. beta 2-微球蛋白:方法和临床应用。  |  Poulik, MD., et al. 1979. CRC Crit Rev Clin Lab Sci. 10: 225-45. PMID: 89022

订购信息

产品名称产品编号规格价格数量收藏夹

β-2-Microglobulin 抗体 (G-10)

sc-46697
200 µg/ml
RMB2377.00

β-2-Microglobulin (G-10): m-IgG Fc BP-HRP 套装

sc-528502
200 µg Ab; 10 µg BP
RMB2662.00

β-2-Microglobulin (G-10): m-IgGκ BP-HRP 套装

sc-520896
200 µg Ab, 40 µg BP
RMB2662.00

β-2-Microglobulin (G-10): m-IgG2a BP-HRP 套装

sc-547110
200 µg Ab; 10 µg BP
RMB2662.00

β-2-Microglobulin 抗体 (G-10) AC

sc-46697 AC
500 µg/ml, 25% agarose
RMB3129.00

β-2-Microglobulin 抗体 (G-10) HRP

sc-46697 HRP
200 µg/ml
RMB2377.00

β-2-Microglobulin 抗体 (G-10) FITC

sc-46697 FITC
200 µg/ml
RMB2482.00

β-2-Microglobulin 抗体 (G-10) PE

sc-46697 PE
200 µg/ml
RMB2580.00

β-2-Microglobulin 抗体 (G-10) Alexa Fluor® 488

sc-46697 AF488
200 µg/ml
RMB2685.00

β-2-Microglobulin 抗体 (G-10) Alexa Fluor® 546

sc-46697 AF546
200 µg/ml
RMB2685.00

β-2-Microglobulin 抗体 (G-10) Alexa Fluor® 594

sc-46697 AF594
200 µg/ml
RMB2685.00

β-2-Microglobulin 抗体 (G-10) Alexa Fluor® 647

sc-46697 AF647
200 µg/ml
RMB2685.00

β-2-Microglobulin 抗体 (G-10) Alexa Fluor® 680

sc-46697 AF680
200 µg/ml
RMB2685.00

β-2-Microglobulin 抗体 (G-10) Alexa Fluor® 790

sc-46697 AF790
200 µg/ml
RMB2685.00

Can β-2-Microglobulin (G-10): sc-46697 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Trav11
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, β-2-Microglobulin (G-10): sc-46697 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_9, d_6, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_46697, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 109ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Great monoclonal antibodybeta-2-Microglobulin Antibody (G-10) showed strong band with very little background and nice IHC stain
Date published: 2017-02-07
Rated 5 out of 5 by from GratefulWe formed MHC class 1 molecules that correctly folded and expressed the immunoglobulin domain - like structure but did not mature to CD4-8 + T cells and needed to continue the study by providing a sense sample
Date published: 2017-01-18
Rated 5 out of 5 by from high affinity and high specificityI check the antibody in decidual macropages by WB, and it shows only one spicific band and could detect the B2M molecule by fewer sample which the antibody from another company could not do it.
Date published: 2016-12-05
Rated 4 out of 5 by from Good signal and appears specificWorks really nicely on PFA fixed free-floating sections as long as you use heat-mediated antigen retrieval. I successfully used this with 30um thick mouse tissue sections pre-incubated in pH6 citrate buffer and microwaved.
Date published: 2016-11-24
Rated 5 out of 5 by from Robust signal in WB in HLRobust signal in WB in HL-60 whole cell lysate. -SCBT QC
Date published: 2015-06-22
Rated 5 out of 5 by from Good specificity in WB in HeLa and 184 wholeGood specificity in WB in HeLa and 184 whole cell lysates. -SCBT QC
Date published: 2015-05-18
Rated 5 out of 5 by from WB publishable data with mouse embryo fibroblastsWB publishable data with mouse embryo fibroblasts - SCBT Publication Review
Date published: 2013-02-07
  • y_2025, m_9, d_6, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_7
  • loc_zh_CN, sid_46697, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 17ms
  • REVIEWS, PRODUCT
β-2-Microglobulin 抗体 (G-10) is rated 4.9 out of 5 by 7.
  • y_2025, m_9, d_6, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_7
  • loc_zh_CN, sid_46697, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 125ms
  • REVIEWS, PRODUCT