Date published: 2025-9-7

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BANK1 抗体 (F-8): sc-393611

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说明书
  • BANK1 抗体 F-8 是小鼠单克隆 IgG1 κ,BANK1抗体, 在1篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列576-785位于human物种的BANK1的C-terminus
  • BANK1 抗体 (F-8) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 BANK1 isoforms 1-4
  • 抗BANK1抗体(F-8)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取BANK1 (F-8): sc-393611免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 BANK1 抗体 (F-8) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与BANK1 抗体 (F-8) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

BANK1抗体(F-8)是一种IgG1 κ小鼠单克隆BANK1抗体(也称为BANK1抗体),可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人类来源的BANK1蛋白。BANK1抗体(F-8)既有非偶联型抗BANK1抗体形式,也有多种偶联型抗BANK1抗体形式,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。BANK1(含锚蛋白重复序列的B细胞支架蛋白)是一种含有1个DBB结构域和2个ANK(锚蛋白)重复序列的785个氨基酸的蛋白质。BANK1在多种B细胞中表达,尤其在CD19(+) B细胞中表达较高,BANK1与Lyn、IP3R-I和IP3R-II相互作用,参与B细胞受体诱导的细胞内钙库钙动员。BANK1通过与Lyn的结合,促进Lyn介导的IP3R-I和IP3R-II的酪氨酸磷酸化,这一事件激活B细胞,可能是体内抗原诱导的免疫反应所必需的。编码BANK1的基因缺陷会增加患系统性红斑狼疮(SLE)的遗传易感性,这是一种影响关节、皮肤、浆膜和肾组织的慢性炎症性疾病。BANK1以四种异构体形式存在,这些异构体由选择性剪接产生。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

BANK1 抗体 (F-8) 参考文献:

  1. BANK 通过促进 IP(3)受体的酪氨酸磷酸化来调节 BCR 诱导的钙动员。  |  Yokoyama, K., et al. 2002. EMBO J. 21: 83-92. PMID: 11782428
  2. BANK 负向调节 Akt 的激活和随后的 B 细胞反应。  |  Aiba, Y., et al. 2006. Immunity. 24: 259-68. PMID: 16546095
  3. B 细胞基因 BANK1 的功能变异与系统性红斑狼疮有关。  |  Kozyrev, SV., et al. 2008. Nat Genet. 40: 211-6. PMID: 18204447
  4. 更正:B 细胞基因 BANK1 的功能变异与系统性红斑狼疮缔合作用。  |  Kozyrev, SV., et al. 2008. Nat Genet. 40: 484. PMID: 18368128

订购信息

产品名称产品编号规格价格数量收藏夹

BANK1 抗体 (F-8)

sc-393611
200 µg/ml
RMB2377.00

BANK1 (F-8): m-IgG Fc BP-HRP 套装

sc-530519
200 µg Ab; 10 µg BP
RMB2662.00

BANK1 (F-8): m-IgGκ BP-HRP 套装

sc-524023
200 µg Ab, 40 µg BP
RMB2662.00

BANK1 (F-8): m-IgG1 BP-HRP 套装

sc-544103
200 µg Ab; 20 µg BP
RMB2662.00

BANK1 抗体 (F-8) AC

sc-393611 AC
500 µg/ml, 25% agarose
RMB3129.00

BANK1 抗体 (F-8) HRP

sc-393611 HRP
200 µg/ml
RMB2377.00

BANK1 抗体 (F-8) FITC

sc-393611 FITC
200 µg/ml
RMB2482.00

BANK1 抗体 (F-8) PE

sc-393611 PE
200 µg/ml
RMB2580.00

BANK1 抗体 (F-8) Alexa Fluor® 488

sc-393611 AF488
200 µg/ml
RMB2685.00

BANK1 抗体 (F-8) Alexa Fluor® 546

sc-393611 AF546
200 µg/ml
RMB2685.00

BANK1 抗体 (F-8) Alexa Fluor® 594

sc-393611 AF594
200 µg/ml
RMB2685.00

BANK1 抗体 (F-8) Alexa Fluor® 647

sc-393611 AF647
200 µg/ml
RMB2685.00

BANK1 抗体 (F-8) Alexa Fluor® 680

sc-393611 AF680
200 µg/ml
RMB2685.00

BANK1 抗体 (F-8) Alexa Fluor® 790

sc-393611 AF790
200 µg/ml
RMB2685.00

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: jerojero
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 15
Date published: 2017-02-10
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Rated 5 out of 5 by from Great resultsA great human specific antibody. It detects multiple isoforms an will provide great staining and blotting data. It is approved for the standard range of applications.
Date published: 2017-01-27
Rated 5 out of 5 by from Produced exceptional immunofluorescence cytoplasmicProduced exceptional immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-02-24
Rated 5 out of 5 by from Nice Western Blot data of BANK1 expression in HeLaNice Western Blot data of BANK1 expression in HeLa, GA-10 and PC-3 whole cell lysates. -SCBT QC
Date published: 2013-06-20
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BANK1 抗体 (F-8) is rated 5.0 out of 5 by 3.
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