Date published: 2026-10-24

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Axl Antibody (B-2) - Western Blotting - Image 291026
Axl 抗体 (B-2): sc-166268. Caki-1 (A) 和 FHs 173We (B) 全细胞裂解液中 Axl 表达的 Western 印迹分析.
Axl 抗体 (B-2): sc-166268. Caki-1 (A) 和 FHs 173We (B) 全细胞裂解液中 Axl 表达的 Western 印迹分析.

Axl 抗体 (B-2): sc-166268

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说明书
  • Axl抗体(B-2)是小鼠单克隆IgG1 κ, 在5篇文献中引用，规格为200 µg/ml
  • 免疫human物种的Axl的氨基酸771-894
  • 推荐用于 human 来源的Axl WB, IP, IF 和 ELISA检测
  • 看 Axl (H-3): sc-166269，可查看有标记的 Axl 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是Axl Antibody (B-2) for WB applications. 的首选辅助检测试剂，这些试剂现与Axl Antibody (B-2) 打包提供（请参阅下面的订购信息）。
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関連項目

受体酪氨酸激酶UFO家族由亚家族成员Rse（也称为Tyro3、Sky、Brt、Dtk、Etk2和Tif）、Axl（也称为UFO或ARK）和Mer（也称为Nyk或Eyk）组成。Rse主要在成年大脑中表达，在其他组织中的表达水平较低。Axl在心脏和骨骼肌中的表达水平最高。Mer已被鉴定为可能参与胶质母细胞瘤发展的酪氨酸激酶。它在卵巢、前列腺、肺和肾中的表达水平最高。生长停滞特异性基因Gas6和相关的抗凝因子蛋白质S已被鉴定为UFO家族受体的配体。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Axl 抗体 (B-2) 参考文献:

  1. Axl抑制剂的研究进展。  |  Sun, ZG., et al. 2019. Curr Top Med Chem. 19: 1338-1349. PMID: 31218961
  2. 白血病性染色质改变通过KDM4C-ALKBH5-AXL信号轴促进急性髓细胞白血病（AML）白血病干细胞的形成。  |  Wang, J., et al. 2020. Cell Stem Cell. 27: 81-97.e8. PMID: 32402251
  3. 巨噬细胞AXL受体酪氨酸激酶在再灌注心肌梗死后引发心脏炎症。  |  DeBerge, M., et al. 2021. J Clin Invest. 131: PMID: 33529176
  4. AXL激酶介导的星形胶质细胞吞噬调节创伤性脑损伤的结果。  |  Zhou, H., et al. 2021. J Neuroinflammation. 18: 154. PMID: 34233703
  5. 加速AXL靶向治疗TNBC。  |  Khera, L. and Lev, S. 2021. Int J Biochem Cell Biol. 139: 106057. PMID: 34403827
  6. Gas6/Axl信号通路在癌症中的治疗靶向。  |  Tanaka, M. and Siemann, DW. 2021. Int J Mol Sci. 22: PMID: 34576116
  7. 以 HER2-AXL 异源二聚体为靶点，克服乳腺癌患者对 HER2 阻断剂的耐药性。  |  Adam-Artigues, A., et al. 2022. Sci Adv. 8: eabk2746. PMID: 35594351
  8. LZTR1突变通过稳定EGFR和AXL来介导肿瘤发生。  |  Ko, A., et al. 2023. Cancer Discov. 13: 702-723. PMID: 36445254
  9. Axl通过STAT1/HIF-1α调节巨噬细胞向M1极化，从而促进颅内动脉瘤破裂。  |  Han, Y., et al. 2023. Front Immunol. 14: 1158758. PMID: 37223093
  10. AXL--HER2阻断抗性中的新角色。  |  Adam-Artigues, A., et al. 2023. Cancer Treat Rev. 121: 102639. PMID: 37864955

订购信息

产品名称产品编号规格价格数量收藏夹

Axl 抗体 (B-2)

sc-166268
200 µg/ml
CNY2422.00

Axl (B-2): m-IgG Fc BP-HRP 套装

sc-540062
200 µg Ab; 10 µg BP
CNY2715.00

Axl (B-2): m-IgG1 BP-HRP 套装

sc-541881
200 µg Ab; 20 µg BP
CNY2715.00

May i request a quote for 1mg, 2.5mg, and 5mg for the AXL antibody in powder form or solution without carrier proteins?

Asked by: shinm
Thank you for your question. Please contact our technical service team directly so we can set up a special order.
Answered by: Tech Support Europe
Date published: 2021-01-13

What is the recommended starting dilution for Western blot for sc-166268: Axl (B-2) monoclonal antibody?

Asked by: Randy McDonald
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 5 out of 5 by waltersjtu from AXL抗体（B-2）的出色表现AXL(B-2)抗体很好，效价高，并且还能重复使用几次，买过好几家的抗体，效果最好的还是B-2，AXL的抗体我推荐圣克鲁斯生物技术（SCBT）。
Date published: 2017-06-02
Rated 5 out of 5 by Germaine from Produced publishable WB dataThis Axl monoclonal antibody was referenced in a recent publication for the use of WB in NSCLC cells (H1299 and A549), pancreatic cancer cells (AsPC-1, Panc-1, and Panc-28), gastric cancer cells (SGC7901 and AGS), glioma cells (LN-18 and LN-229), breast cancer cells (MDA-MB-231), colon cancer cells (HCT116), cervical carcinoma cells (HeLa cells), MEFs and HEK293T whole cell lysate
Date published: 2017-01-26
Rated 5 out of 5 by JT from Good Western Blot data of Axl expression in nonGood Western Blot data of Axl expression in non-transfected and human Axl transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-04-05
Rated 5 out of 5 by SM from Nice Western Blot data of Axl expression in CakiNice Western Blot data of Axl expression in Caki-1 and FHs 173We whole cell lysates. -SCBT QC
Date published: 2013-10-20
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Axl 抗体 (B-2) is rated 5.0 out of 5 by 4.
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