Date published: 2026-10-24

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ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 Antibody (A-5) - Western Blotting - Image 299149
ASGPR1 抗体 (A-5): sc-393849. Hep G2 全细胞裂解液 (A) 和人肝组织提取物 (B) 中 ASGPR1 表达的 Western 印迹分析.
ASGPR1 抗体 (A-5): sc-393849. Hep G2 全细胞裂解液 (A) 和人肝组织提取物 (B) 中 ASGPR1 表达的 Western 印迹分析.

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5): sc-393849

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说明书
  • ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 A-5 是小鼠单克隆 IgG1 κ，ASGPR1/Asialoglycoprotein Receptor 1/ASGR1抗体, 在1篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于human物种的ASGPR1的N-terminus的氨基酸2-27之间
  • ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) 推荐用于WB, IP, IF 和 ELISA，检测human 来源的 ASGPR1
  • 抗ASGPR1/Asialoglycoprotein Receptor 1/ASGR1抗体（A-5）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 Antibody (A-5) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 Antibody (A-5) 打包提供（请参阅下面的订购信息）。
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関連項目

额外ASGPR抗体，包括ASGPR2

ASGPR1抗体（A-5）是一种IgG1 κ小鼠单克隆ASGPR1抗体（也称为ASGR1抗体、无唾液酸糖蛋白受体1抗体或异寡聚体无唾液酸糖蛋白受体主要亚基1抗体），可通过WB、IP、IF和ELISA检测人类来源的ASGPR1蛋白。ASGPR1抗体（A-5）既可以作为非偶联的抗ASGPR1抗体形式，也可以作为多种偶联形式的抗ASGPR1抗体，包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。无唾液酸糖蛋白受体（ASGPR，也称为肝凝集素）是一种II型整合膜蛋白，在肝细胞中表达。ASGPR由两个同源亚基ASGPR1和ASGPR2组成，它们形成多聚体复合物。ASGPR1和ASGPR2都包含四个功能域，包括胞质域、跨膜域、茎域和碳水化合物识别域（CRD）。CRD允许ASGPR在钙存在的情况下与具有末端半乳糖和N-乙酰半乳糖胺残基的糖蛋白结合。结合后，ASGPR-糖蛋白复合物被内化到细胞中，受体和配体解离，ASGPR返回细胞膜。ASGPR还可以结合乙型肝炎病毒（HBV）并介导HBV感染肝细胞。与HBV的特异性相互作用使ASGPR成为潜在的治疗靶点。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) 参考文献:

  1. 大分子药物的靶向递送：抗病毒药物研发中使用的特定肝癌细胞系中的糖蛋白受体（ASGPR）表达。  |  Li, Y., et al. 2008. Curr Drug Deliv. 5: 299-302. PMID: 18855599
  2. 通过糖蛋白受体（ASGPR）靶向递送阿托伐他汀。  |  Zhang, Y., et al. 2019. Bioorg Med Chem. 27: 2187-2191. PMID: 31005367
  3. Recent Advances in Asialoglycoprotein Receptor and Glycyrrhetinic Acid Receptor-Mediated and/or pH-Responsive Hepatocellular Carcinoma- Targeted Drug Delivery.  |  Li, YL., et al. 2021. Curr Med Chem. 28: 1508-1534. PMID: 32368967
  4. 以糖蛋白受体为靶点的超顺磁全氟辛基溴化物纳米粒子。  |  Li, Y., et al. 2021. Contrast Media Mol Imaging. 2021: 5510071. PMID: 34131415
  5. Asialoglycoprotein Receptor 1 Functions as a Tumor Suppressor in Liver Cancer via Inhibition of STAT3.  |  Zhu, X., et al. 2022. Cancer Res. 82: 3987-4000. PMID: 36043912
  6. 通过异二官能团配体介导的糖蛋白受体清除血浆PCSK9。  |  Bagdanoff, JT., et al. 2023. Cell Chem Biol. 30: 97-109.e9. PMID: 36626903
  7. 半乳糖蛋白受体和甘露糖受体缺乏对小鼠血浆N-糖苷化谱的影响。  |  Svecla, M., et al. 2023. Mol Cell Proteomics. 22: 100615. PMID: 37414249
  8. Asialoglycoprotein receptor 1 promotes SARS-CoV-2 infection of human normal hepatocytes.  |  Yang, X., et al. 2024. Signal Transduct Target Ther. 9: 42. PMID: 38355848
  9. 针对肝核医学成像的半乳糖蛋白受体靶向放射性示踪剂的研究进展。  |  Hua, Y. and Yu, C. 2024. Eur J Med Chem. 269: 116278. PMID: 38479165
  10. 通过糖蛋白受体靶向肝细胞。  |  Ramírez-Cortés, F. and Ménová, P. 2024. RSC Med Chem.. PMID: 39628900

订购信息

产品名称产品编号规格价格数量收藏夹

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5)

sc-393849
200 µg/ml
CNY2422.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 (A-5): m-IgG Fc BP-HRP 套装

sc-530604
200 µg Ab; 10 µg BP
CNY2715.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 (A-5): m-IgGκ BP-HRP 套装

sc-524118
200 µg Ab, 40 µg BP
CNY2715.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 (A-5): m-IgG1 BP-HRP 套装

sc-544158
200 µg Ab; 20 µg BP
CNY2715.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) AC

sc-393849 AC
500 µg/ml, 25% agarose
CNY3189.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) HRP

sc-393849 HRP
200 µg/ml
CNY2422.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) FITC

sc-393849 FITC
200 µg/ml
CNY2527.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) PE

sc-393849 PE
200 µg/ml
CNY2625.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) Alexa Fluor® 488

sc-393849 AF488
200 µg/ml
CNY2738.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) Alexa Fluor® 546

sc-393849 AF546
200 µg/ml
CNY2738.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) Alexa Fluor® 594

sc-393849 AF594
200 µg/ml
CNY2738.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) Alexa Fluor® 647

sc-393849 AF647
200 µg/ml
CNY2738.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) Alexa Fluor® 680

sc-393849 AF680
200 µg/ml
CNY2738.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) Alexa Fluor® 790

sc-393849 AF790
200 µg/ml
CNY2738.00

ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 (A-5) 中和勝肽

sc-393849 P
100 µg/0.5 ml
CNY519.00

What application is the blocking peptide sc-393849 P appropriate for?

Asked by: Dr Ninau Qelp
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by hanyan from specific bandAppearted one specific band on membrance for human livert tissue extracts. Dilution is 1:1000.
Date published: 2017-06-11
Rated 5 out of 5 by cjMara from Good choice for WBWe have had successful results using this antibody in Hep G2 whole cell lysate, and human liver tissue extract at a dilution of 1:200.
Date published: 2017-02-01
Rated 5 out of 5 by wxy005987 from good resultI have used the antibody for more than 4 times, and the result is quite satisfied (except one time, maybe polluted), my teacher has praised me for my beautiful result!!
Date published: 2016-11-21
Rated 5 out of 5 by MC from Very good Western blot data of ASGPR1 expressionVery good Western blot data of ASGPR1 expression in Hep G2 whole cell lysate and human liver tissue extract . -SCBT QC
Date published: 2014-11-25
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ASGPR1/Asialoglycoprotein Receptor 1/ASGR1 抗体 (A-5) is rated 5.0 out of 5 by 4.
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