Date published: 2025-9-8
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ARG1/Arginase 1 Antibody (C-2) - Western Blotting - Image 379248
精氨酸酶 1 抗体 (C-2): sc-166920. 人肝 (A) 和人胎肝 (B) 组织提取物中精氨酸酶 1 表达的 Western 印迹分析.
精氨酸酶 1 抗体 (C-2): sc-166920. 人肝 (A) 和人胎肝 (B) 组织提取物中精氨酸酶 1 表达的 Western 印迹分析.

ARG1/Arginase 1 抗体 (C-2): sc-166920

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说明书
  • ARG1/Arginase 1 抗体 C-2 是小鼠单克隆 IgG2b κ，ARG1/Arginase 1抗体, 在44篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于human物种的arginase I的N-terminus附近的氨基酸46-65之间
  • ARG1/Arginase 1 抗体 (C-2) 推荐用于WB, IP, IF, IHC(P) 和 ELISA，检测human 来源的 Arginase 1
  • 抗ARG1/Arginase 1抗体（C-2）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取ARG1/Arginase 1 (C-2): sc-166920的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG2b BP-HRP 和 m-IgGκ BP-HRP 是 ARG1/Arginase 1 抗体 (C-2) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与ARG1/Arginase 1 抗体 (C-2) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 Arginase 抗体 包括 Arg2

Arginase 1抗体（C-2）是一种IgG2b κ小鼠单克隆精氨酸酶I抗体（也称为Arginase-1抗体或肝精氨酸酶抗体），可通过WB、IP、IF、IHC(P)和ELISA检测人源精氨酸酶I蛋白。Arginase I抗体（C-2）既可以非偶联抗精氨酸酶I抗体的形式提供，也可以多种偶联形式的抗精氨酸酶I抗体提供，包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。精氨酸酶I（也称为肝型精氨酸酶）几乎只在肝脏中表达，催化精氨酸转化为鸟氨酸和尿素。精氨酸酶I以同源三聚体蛋白的形式存在，并含有一个双核锰簇。精氨酸酶II催化与精氨酸酶I相同的反应，但在组织特异性和亚细胞定位上有所不同。具体来说，精氨酸酶II定位于线粒体。精氨酸酶II在非肝组织中表达，在肾脏中的表达水平最高，但与精氨酸酶I不同，它不在肝脏中表达。此外，精氨酸酶II含有一个假定的氨基末端线粒体定位序列。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

ARG1/Arginase 1 抗体 (C-2) 参考文献:

  1. 人类精氨酸酶四元结构中 S 形结构域的含义。  |  Mora, A., et al. 2000. Biochim Biophys Acta. 1476: 181-90. PMID: 10669784
  2. 精氨酸酶的结构和功能。  |  Ash, DE. 2004. J Nutr. 134: 2760S-2764S; discussion 2765S-2767S. PMID: 15465781
  3. 通过饮食中缺锰来降低精氨酸酶的活性，可增强大鼠主动脉内皮依赖性血管舒张。  |  Ensunsa, JL., et al. 2004. Exp Biol Med (Maywood). 229: 1143-53. PMID: 15564441
  4. 肝脏精氨酸酶缺乏导致的高精氨酸血症。  |  Crombez, EA. and Cederbaum, SD. 2005. Mol Genet Metab. 84: 243-51. PMID: 15694174
  5. 监测肝移植后肝细胞功能的精氨酸酶活性浓度标记--初步报告。  |  Grodzicki, M., et al. 2004. Ann Transplant. 9: 54-7. PMID: 15759549
  6. 经肝动脉栓塞引起的内源性肝脏精氨酸酶全身释放诱导的精氨酸耗竭性肝细胞癌缓解，大剂量胰岛素增强了这种缓解：精氨酸酶是治疗肝细胞癌的潜在候选药物。  |  Cheng, PN., et al. 2005. Cancer Lett. 224: 67-80. PMID: 15911102
  7. 肝脏精氨酸酶两种不同分子质量组成亚基的免疫学特性。  |  Diez, A., et al. 1994. Biol Chem Hoppe Seyler. 375: 537-41. PMID: 7811393
  8. 非肝脏线粒体精氨酸酶（精氨酸酶 II）cDNA 的分子克隆及其在小鼠巨噬细胞样细胞系中与一氧化氮合酶诱导作用的比较。  |  Gotoh, T., et al. 1996. FEBS Lett. 395: 119-22. PMID: 8898077
  9. 人类精氨酸酶 II 基因的染色体定位及其 mRNA 的组织分布。  |  Gotoh, T., et al. 1997. Biochem Biophys Res Commun. 233: 487-91. PMID: 9144563
  10. 败血症患者肺部精氨酸酶和 iNOS 的差异表达。  |  Carraway, MS., et al. 1998. Exp Lung Res. 24: 253-68. PMID: 9635249

订购信息

产品名称产品编号规格价格数量收藏夹

ARG1/Arginase 1 抗体 (C-2)

sc-166920
200 µg/ml
RMB2377.00

ARG1/Arginase 1 (C-2): m-IgGκ BP-HRP 套装

sc-521800
200 µg Ab, 40 µg BP
RMB2662.00

ARG1/Arginase 1 (C-2): m-IgG2b BP-HRP 套装

sc-548968
200 µg Ab; 10 µg BP
RMB2662.00

ARG1/Arginase 1 抗体 (C-2) AC

sc-166920 AC
500 µg/ml, 25% agarose
RMB3129.00

ARG1/Arginase 1 抗体 (C-2) HRP

sc-166920 HRP
200 µg/ml
RMB2377.00

ARG1/Arginase 1 抗体 (C-2) FITC

sc-166920 FITC
200 µg/ml
RMB2482.00

ARG1/Arginase 1 抗体 (C-2) PE

sc-166920 PE
200 µg/ml
RMB2580.00

ARG1/Arginase 1 抗体 (C-2) Alexa Fluor® 488

sc-166920 AF488
200 µg/ml
RMB2685.00

ARG1/Arginase 1 抗体 (C-2) Alexa Fluor® 546

sc-166920 AF546
200 µg/ml
RMB2685.00

ARG1/Arginase 1 抗体 (C-2) Alexa Fluor® 594

sc-166920 AF594
200 µg/ml
RMB2685.00

ARG1/Arginase 1 抗体 (C-2) Alexa Fluor® 647

sc-166920 AF647
200 µg/ml
RMB2685.00

ARG1/Arginase 1 抗体 (C-2) Alexa Fluor® 680

sc-166920 AF680
200 µg/ml
RMB2685.00

ARG1/Arginase 1 抗体 (C-2) Alexa Fluor® 790

sc-166920 AF790
200 µg/ml
RMB2685.00

ARG1/Arginase 1 (C-2) 中和勝肽

sc-166920 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-166920 P appropriate for?

Asked by: DefinitelyNotMatt
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by from Good antibody for western blotI used this antibody in western blot of human microglial cell. I obtained a specific band according to the datasheet with no background.
Date published: 2021-11-23
Rated 1 out of 5 by from This antibody did not workI used this antibody for immunostaining somehow it did not work in my experiment.
Date published: 2021-10-29
Rated 5 out of 5 by from stable resultGood quality antibody for WB, very stable and use for WB 1:2000 dilution.
Date published: 2017-02-09
Rated 5 out of 5 by from The effect is very good.Good specificity in WB in Caki-1 whole cell lysate.
Date published: 2017-02-08
Rated 5 out of 5 by from It is Very Clear in Western Blotingarginase I antibody works well, antibody shows hight express in human spleen tissue.
Date published: 2017-02-06
Rated 5 out of 5 by from Produced publishable WB data on h, m and rThis well characterized arginase I monoclonal antibody has been featured in a handful of publications for the use of WB on human, mouse and rat samples.
Date published: 2017-01-18
Rated 5 out of 5 by from greatWorks well for immunofluorescence studies, cytoplasmic staining in HeLa cells
Date published: 2016-10-28
Rated 5 out of 5 by from Used in WB and worked really well at 1:500Used in WB and worked really well at 1:500 dilution.
Date published: 2015-06-18
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ARG1/Arginase 1 抗体 (C-2) is rated 4.5 out of 5 by 12.
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