Date published: 2025-9-8

021-6093-6350

SCBT Portrait Logo
Seach Input

Aquaporin 2/AQP2 抗体 (E13-21): sc-47710

4.0(6)
寫評論提問

说明书
  • Aquaporin 2/AQP2抗体(E13-21)是小鼠单克隆IgM κ, 在5篇文献中引用,规格为200 µg/ml
  • 针对AQP2的rat起源的C-terminus的
  • 抗-Aquaporin 2/AQP2 抗体 (E13-21) 推荐用于 WB, IP 和 IF,检测mouse, rat 和human 来源的 AQP2
  • Aquaporin 2/AQP2抗体(E13-21)可与Alexa Fluor® 546Alexa Fluor® 594结合,用于WB(RGB)、IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Aquaporin 2/AQP2 (E13-21): sc-47710免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgGκ BP-HRP是Aquaporin 2/AQP2 Antibody (E13-21) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现可与Aquaporin 2/AQP2 Antibody (E13-21) 搭配使用(请参阅下面的订购信息)。有关其它 m-IgGκ BP 结合物,请参阅我们完整的小鼠 IgG 结合蛋白列表。

快捷链接

関連項目

Aquaporin 2/AQP2抗体(E13-21)是一种IgM κ小鼠单克隆AQP2抗体,可通过WB和IF检测来自小鼠、大鼠和人类的AQP2。Aquaporin 2/AQP2抗体(E13-21)既可以是非偶联的,也可以是多种偶联形式的抗AQP2抗体。Aquaporin(AQP)是一大类细胞膜内水转运通道蛋白,促进细胞膜内水分子的转运。这一功能在动物、植物和细菌中都得到保留。哺乳动物中已经鉴定出许多AQP异构体,分别称为AQP0至AQP10。Aquaporin在各处分布,同一细胞中存在多种AQP类型并不少见。尽管大多数Aquaporin只对水分子有通透性,但AQP3、AQP7、AQP9和AQP10的两个转录本中的一个也对尿素和甘油有通透性。AQP2是唯一一种受到肾上腺素激活以增强肾小管吸收的水通道。Aquaporin参与肾脏水分吸收、肺泡分泌物的产生、泪液分泌和脑脊液的分泌和再吸收以及眼液的分泌和再吸收。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Aquaporin 2/AQP2 抗体 (E13-21) 参考文献:

  1. 哺乳动物水通道蛋白家族:有希望的新药靶点  |  Beitz, E. and Schultz, JE. 1999. Curr Med Chem. 6: 457-67. PMID: 10213793
  2. 分离出 28 千道尔顿的红细胞整体膜蛋白 cDNA:古老通道家族的成员。  |  Preston, GM. and Agre, P. 1991. Proc Natl Acad Sci U S A. 88: 11110-4. PMID: 1722319
  3. 微肽MIAC通过与AQP2相互作用并抑制肾细胞癌中的EREG/EGFR信号传导来抑制肿瘤进展。  |  Li, M., et al. 2022. Mol Cancer. 21: 181. PMID: 36117171
  4. 蛋白质组学与AQP2调节。  |  Yang, CR., et al. 2024. J Physiol. 602: 3011-3023. PMID: 36571566
  5. LRBA信号体激活血管加压素诱导的AQP2在循环内体的贩运。  |  Yanagawa, H., et al. 2023. J Physiol. 601: 5437-5451. PMID: 37860942
  6. 人集合管水蒸发素的克隆, 表征和染色体图谱。  |  Sasaki, S., et al. 1994. J Clin Invest. 93: 1250-6. PMID: 7510718
  7. 人类水通道(AQP3)基因的结构和染色体定位。  |  Ishibashi, K., et al. 1995. Genomics. 27: 352-4. PMID: 7558005
  8. 人类汞不敏感水通道的 cDNA 克隆, 基因组织和染色体定位。不同转录单元的证据。  |  Yang, B., et al. 1995. J Biol Chem. 270: 22907-13. PMID: 7559426
  9. 人体肾脏水通道 aquaporin-2 对血管加压素依赖性尿液浓缩的要求。  |  Deen, PM., et al. 1994. Science. 264: 92-5. PMID: 8140421
  10. 人类 Aquaporin-5 基因。分子特征和染色体定位。  |  Lee, MD., et al. 1996. J Biol Chem. 271: 8599-604. PMID: 8621489
  11. 稳定转染 AQP2 的人类集合管细胞系中水通道的表达和功能分析。  |  Valenti, G., et al. 1996. J Biol Chem. 271: 24365-70. PMID: 8798691
  12. 水通道蛋白。  |  Echevarría, M. and Ilundáin, AA. 1998. J Physiol Biochem. 54: 107-18. PMID: 9858131

订购信息

产品名称产品编号规格价格数量收藏夹

Aquaporin 2/AQP2 抗体 (E13-21)

sc-47710
200 µg/ml
RMB2377.00

Aquaporin 2/AQP2 (E13-21): m-IgGκ BP-HRP 套装

sc-551218
200 µg Ab; 40 µg BP
RMB2662.00

Aquaporin 2/AQP2 抗体 (E13-21) Alexa Fluor® 546

sc-47710 AF546
200 µg/ml
RMB2685.00

Aquaporin 2/AQP2 抗体 (E13-21) Alexa Fluor® 594

sc-47710 AF594
200 µg/ml
RMB2685.00

Aquaporin 2/AQP2 抗体 (E13-21) Alexa Fluor® 680

sc-47710 AF680
200 µg/ml
RMB2685.00

Aquaporin 2/AQP2 抗体 (E13-21) Alexa Fluor® 790

sc-47710 AF790
200 µg/ml
RMB2685.00

is antigen retrieval required?

Asked by: wwwy
Thank you for your question. We always recommend performing antigen retrieval if fixing in formalin or PFA. Please contact our Technical Service Department for further recommendations regarding this specific antibody.
Answered by: Technical Support
Date published: 2019-06-16

What is the recommended starting dilution for Western blot for AQP2 (E13-21): sc-47710 monoclonal antibody?

Asked by: jenniferc
Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-47710.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
Answered by: Technical Support
Date published: 2017-01-24
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_47710, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 118ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from strong signalUsed for WB and paraffin-embedded IHC with rat kidney samples,both very strong signal.
Date published: 2017-04-15
Rated 5 out of 5 by from Extremely strong AQP2 antibody!This antibody is a very smart choice for studying AQP2. Solid and reliable.
Date published: 2016-12-20
Rated 5 out of 5 by from Perfect.Worked great in IHC on parrafin embedded sections. Green = AQP2, Blue=DAPI.
Date published: 2016-11-28
Rated 1 out of 5 by from Does not work for IP, western or IHC (paraffin)Tried multiple times to get it to work - awful. Used AQP2 antibodies for 15 years and this is the worse
Date published: 2016-09-20
Rated 4 out of 5 by from Good data obtained by immunohistochemistryGood data obtained by immunohistochemistry using human kidney tissue. -SCBT Publication Review
Date published: 2015-02-25
Rated 4 out of 5 by from Publishable data obtained by immunohistochemistryPublishable data obtained by immunohistochemistry (p) using mouse kidney. -SCBT Publication Review
Date published: 2013-11-26
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_6
  • loc_zh_CN, sid_47710, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 18ms
  • REVIEWS, PRODUCT
Aquaporin 2/AQP2 抗体 (E13-21) is rated 4.0 out of 5 by 6.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_6
  • loc_zh_CN, sid_47710, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 111ms
  • REVIEWS, PRODUCT