Date published: 2025-9-8

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APC 抗体 (A-3): sc-393704

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说明书
  • APC抗体(A-3)是小鼠单克隆IgG2b κ, 在4篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的APC的N-terminus的氨基酸2-19之间
  • 推荐用于 mouse, rat, human 和 avian 来源的APC WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine, bovine, porcine and avian
  • 看 APC (F-3): sc-9998,可查看有标记的 APC 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是APC Antibody (A-3) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与APC Antibody (A-3) 打包提供(请参阅下面的订购信息)。

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関連項目

腺瘤性息肉综合征、家族性腺瘤性息肉病(FAP)和加德纳综合征(GS)的特征是整个结肠内有许多腺瘤性息肉。除了其他结肠外表现外,这些息肉总是发展为癌症。APC基因的克隆揭示了一种广泛表达的蛋白质,长度为2,843个氨基酸,在患有FAP和GS的患者中经常发生突变。 APC已被发现与细胞内连接的结构成分有关。β-连环蛋白和γ-连环蛋白(也称为斑球蛋白)参与细胞粘附的调节。APC和E-钙粘蛋白竞争结合β-和γ-连环蛋白的特定内部区域。细胞骨架与APC、E-钙粘蛋白、β/γ连接蛋白复合物之间的相互作用由α-连接蛋白介导。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

APC 抗体 (A-3)

sc-393704
200 µg/ml
RMB2377.00

APC (A-3): m-IgG Fc BP-HRP 套装

sc-538286
200 µg Ab; 10 µg BP
RMB2662.00

APC (A-3): m-IgGκ BP-HRP 套装

sc-535867
200 µg Ab; 40 µg BP
RMB2662.00

APC (A-3): m-IgG2b BP-HRP 套装

sc-549933
200 µg Ab; 10 µg BP
RMB2662.00

APC (A-3) 中和勝肽

sc-393704 P
100 µg/0.5 ml
RMB511.00

Hello. I need an antiboy for APC. My question is, This antibody (SC-393704) recognize the truncated and full lenght for of APC? I need to study both forms. I prefer one antibody recognizing both form and work for western blot and Immunoprecipitation.

Asked by: ali jose calderon
Thank you for your question. APC Antibody (A-3): sc-393704 is specific for an epitope mapping between amino acids 2-19 at the N-terminus of APC of human origin. According to Uniprot (http://www.uniprot.org/uniprot/P25054#sequences), the short isoform of APC is missing amino acids 312-412. Therefore, this antibody has an epitope that can recognize both the long and short isoforms of APC. However, we have not confirmed this experimentally. The difference in the predicted molecular weights of the isoform is only roughly 11 kDa. This antibody is recommended for Western blot and immunoprecipitation.
Answered by: Technical Support
Date published: 2024-05-14

What application is the blocking peptide sc-393704 P appropriate for?

Asked by: Professor Griffin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from consistent western blot band resultWe used this antibody for western blot staining and got a nice consistent western blot band at the correct molecular weight
Date published: 2017-01-27
Rated 5 out of 5 by from Produced positive Western Blot data of APCProduced positive Western Blot data of APC expression in HT-29 whole cell lysate. -SCBT QC
Date published: 2015-01-10
Rated 5 out of 5 by from Produced positive Western Blot data of APCProduced positive Western Blot data of APC expression in COLO 205 whole cell lysate. -SCBT QC
Date published: 2014-09-19
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APC 抗体 (A-3) is rated 5.0 out of 5 by 3.
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