Date published: 2025-9-9

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Amphiregulin 抗体 (C-1): sc-393433

5.0(1)
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说明书
  • Amphiregulin抗体(C-1)是小鼠单克隆IgG2a κ, 在1篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Amphiregulin的C-terminus附近的氨基酸161-185之间
  • 推荐用于 mouse, rat 和 human 来源的precursor and mature Amphiregulin WB, IP, IF 和 ELISA检测
  • 看 Amphiregulin (G-4): sc-74501,可查看有标记的 Amphiregulin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是Amphiregulin Antibody (C-1) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Amphiregulin Antibody (C-1) 打包提供(请参阅下面的订购信息)。

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関連項目

表皮生长因子(EGF)家族成员Amphiregulin最初被表征为神经鞘瘤衍生生长因子(SDGF),它是在SC2G小鼠细胞系中响应雄激素而表达的。随后,Amphiregulin被表征为正常人类角质形成细胞增殖的重要生长因子。Amphiregulin由角质形成细胞产生并分泌,并作为自分泌生长因子发挥作用。Amphiregulin与ErbB-1结合,ErbB-1对于皮肤、肺和胃肠道的上皮发育至关重要。已显示Amphiregulin的撤退会导致人角质形成细胞中端粒酶活性的下调,这表明Amphiregulin在细胞衰老中发挥作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Amphiregulin 抗体 (C-1) 参考文献:

  1. 安非拉酮是组织纤维化的驱动因素。  |  Zaiss, DMW. 2020. Am J Transplant. 20: 631-632. PMID: 31833651
  2. 安非拉酮调节黑色素细胞的衰老  |  Pommer, M., et al. 2021. Cells. 10: PMID: 33562468
  3. 安非他酮胰岛素通过表皮生长因子受体依赖途径在肺上皮细胞中通过 TGF-β 诱导 CCN2 和纤连蛋白的表达。  |  Cheng, WH., et al. 2022. Respir Res. 23: 381. PMID: 36578010
  4. 两性胰岛素在卵巢功能和疾病中的作用。  |  Fang, L., et al. 2023. Cell Mol Life Sci. 80: 60. PMID: 36749397
  5. Amphiregulin可将IL1RL1+调节性T细胞与癌症相关成纤维细胞结合起来,从而阻碍抗肿瘤免疫。  |  Sun, R., et al. 2023. Sci Adv. 9: eadd7399. PMID: 37611111
  6. 谷氨酰胺代谢控制着人类软骨肉瘤对顺铂的化疗抗性。  |  Wu, YY., et al. 2023. Int J Biol Sci. 19: 5174-5186. PMID: 37928274
  7. 表达 Granzyme K- 和 amphiregulin 的细胞毒性 T 细胞和活化的滤泡外 B 细胞是 IgG4 相关疾病的潜在驱动因素。  |  Koga, R., et al. 2024. J Allergy Clin Immunol. 153: 1095-1112. PMID: 38092138
  8. 安非他酮通过调节自噬和细胞凋亡改善心肌梗死后的心室重塑  |  Li, N., et al. 2024. FASEB J. 38: e23488. PMID: 38358359
  9. 在胃黏膜再生过程中,双链调节蛋白可改变祖细胞命运,促进细胞系分化。  |  Lee, SH., et al. 2024. Gastroenterology. 167: 469-484. PMID: 38492892
  10. 应激诱导的Rab11a-外泌体在结直肠癌中诱导安非他酮介导的西妥昔单抗抗药性。  |  Mason, JD., et al. 2024. J Extracell Vesicles. 13: e12465. PMID: 38887984

订购信息

产品名称产品编号规格价格数量收藏夹

Amphiregulin 抗体 (C-1)

sc-393433
200 µg/ml
RMB2377.00

Amphiregulin (C-1): m-IgG Fc BP-HRP 套装

sc-538215
200 µg Ab; 10 µg BP
RMB2662.00

Amphiregulin (C-1): m-IgGκ BP-HRP 套装

sc-535783
200 µg Ab; 40 µg BP
RMB2662.00

Amphiregulin (C-1): m-IgG2a BP-HRP 套装

sc-548234
200 µg Ab; 10 µg BP
RMB2662.00

Amphiregulin (C-1) 中和勝肽

sc-393433 P
100 µg/0.5 ml
RMB511.00

I want to use sc-393433 for sandwich ELISA assay. please let me know what is pair antibody with sc-393433

Asked by: JKang
Thank you for your question. We do not support our products for sandwich ELISA, so we have not paired this Amphiregulin (C-1) monoclonal antibody with any other antibodies. We do offer one other Amphiregulin antibody, sc-393433, but we have not used them together for sandwich ELISA and can not warranty them for this use.
Answered by: Tech Service
Date published: 2020-01-15

What application is the blocking peptide sc-393433 P appropriate for?

Asked by: TinTin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Very good Western blot data of AmphiregulinVery good Western blot data of Amphiregulin expression in HeLa whole cell lysate. -SCBT QC
Date published: 2013-07-16
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Amphiregulin 抗体 (C-1) is rated 5.0 out of 5 by 1.
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