Date published: 2025-9-9

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Amphiphysin I 抗体 (B-6): sc-390338

5.0(2)
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说明书
  • Amphiphysin I抗体(B-6)是小鼠单克隆IgM (kappa轻链),规格为200 µg/ml
  • 免疫human物种的amphiphysin I的氨基酸467-620
  • 推荐用于 human 来源的Amphiphysin I WB, IP, IF 和 ELISA检测
  • 目前,我们还没有完成Amphiphysin I 抗体 (B-6)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    Amphiphysin是一种富含于大脑中的蛋白质,表现出N-末端脂质相互作用并作为二聚体发挥作用。Amphiphysin包含一个膜弯曲BAR结构域、一个中间Clathrin和适配器结合结构域以及一个C-末端SH3结构域。在大脑中,Amphiphysin I和II形成异二聚体,通过它们的SH3结构域与Clathrin相关的GTPase Dynamin结合。这种关联对于神经元中突触囊泡的循环至关重要,因为它先于Dynamin与Clathrin涂层坑的结合和随后的囊泡出芽。在其他组织中,Amphiphysin可能在其他膜弯曲和曲率稳定事件中发挥关键作用。哺乳动物Amphiphysins,即Amphiphysin I和Amphiphysin II,具有相似的总体结构。Amphiphysin II的一种普遍存在的剪接形式不包含Clathrin或适配器相互作用,在肌肉组织中高度表达,并参与T小管网络的形成和稳定。

    仅限研究使用。不适用于诊断和治疗用途。

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    Amphiphysin I 抗体 (B-6)

    sc-390338
    200 µg/ml
    RMB2377.00

    What is the recommended fixation method for immunofluorescence staining with Amphiphysin I (B-6): sc-390338 monoclonal antibody?

    Asked by: Trav11
    Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from Beautiful immunofluorescence cytoplasmicBeautiful immunofluorescence cytoplasmic and membrane staining in methanol-fixed HeLa cells. -SCBT QC
    Date published: 2015-02-19
    Rated 5 out of 5 by from Nice Western Blot data of Amphiphysin I expressionNice Western Blot data of Amphiphysin I expression in human hippocampus tissue extract and IMR-32 whole cell lysate . -SCBT QC
    Date published: 2013-06-22
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    Amphiphysin I 抗体 (B-6) is rated 5.0 out of 5 by 2.
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