Date published: 2025-9-9

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Amphiphysin I 抗体 (15): sc-135830

4.0(1)
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说明书
  • Amphiphysin I 抗体 15 是小鼠单克隆 IgG1,提供 50 µg/500 µl
  • 免疫human物种的Amphiphysin I的氨基酸258-414
  • 推荐用于 mouse, rat 和 human 来源的Amphiphysin I WB, IP, IF 和 IHC(P)检测; 不建议用于IP
  • 目前,我们还没有完成Amphiphysin I 抗体 (15)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    Amphiphysin是一种富含于大脑中的蛋白质,表现出N-末端脂质相互作用并作为二聚体发挥作用。Amphiphysin包含一个膜弯曲BAR结构域、一个中间Clathrin和适配器结合结构域以及一个C-末端SH3结构域。在大脑中,Amphiphysin I和II形成异二聚体,通过它们的SH3结构域与Clathrin相关的GTPase Dynamin结合。这种关联对于神经元中突触囊泡的循环至关重要,因为它先于Dynamin与Clathrin涂层坑的结合和随后的囊泡出芽。在其他组织中,Amphiphysin可能在其他膜弯曲和曲率稳定事件中发挥关键作用。哺乳动物Amphiphysins,即Amphiphysin I和Amphiphysin II,具有相似的总体结构。Amphiphysin II的一种普遍存在的剪接形式不包含Clathrin或适配器相互作用,在肌肉组织中高度表达,并参与T小管网络的形成和稳定。

    仅限研究使用。不适用于诊断和治疗用途。

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    Amphiphysin I 抗体 (15)

    sc-135830
    50 µg/500 µl
    RMB2377.00

    Can sc-135830: Amphiphysin I (15) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: cjMara
    Thank you for your question. Yes, sc-135830: Amphiphysin I (15) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-03-24
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    Rated 4 out of 5 by from Nice results in western blot analysis ofNice results in western blot analysis of Amphiphysin I expression in rat cerebrum tissue extract. -SCBT QC
    Date published: 2014-10-12
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    Amphiphysin I 抗体 (15) is rated 4.0 out of 5 by 1.
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