Date published: 2025-9-6

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Alkaline Phosphatase 抗体 (G-9): sc-398461

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说明书
  • Alkaline Phosphatase抗体(G-9)是小鼠单克隆IgG1 κ, 在10篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列31-330位于human物种的PLAP的N-terminus附近
  • 推荐用于 mouse, rat 和 human 来源的PLAP, ALPPL2 and IAP WB, IP, IF 和 ELISA检测
  • 看 PLAP (8B6): sc-47691,可查看有标记的 Alkaline Phosphatase 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Alkaline Phosphatase Antibody (G-9) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Alkaline Phosphatase Antibody (G-9) 打包提供(请参阅下面的订购信息)。

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関連項目

碱性磷酸酶(AP)是糖基-磷脂酰肌醇(GPI)锚定的、二聚体的、Zn2+金属化的糖蛋白,可催化磷酸单酯水解为无机磷酸和醇。胎盘碱性磷酸酶(也称为PLAP、ALPP、PALP、胎盘ALP-1或Regan同工酶)是一种由530个氨基酸组成的组织特异性AP,在胎盘、孕妇血清中表达,并在各种癌症中异位表达,包括卵巢和睾丸癌症。PLAP可能有助于引导迁移细胞和运输特定分子(如脂肪酸和免疫球蛋白)穿过细胞膜。在人类中已发现的三种组织特异性AP,即PLAP、生殖细胞AP(GCAP)和肠AP,具有90-98%的同源性,且它们的基因聚集在2号染色体2q上。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Alkaline Phosphatase 抗体 (G-9) 参考文献:

  1. 碱性磷酸酶的结构和机制。  |  Coleman, JE. 1992. Annu Rev Biophys Biomol Struct. 21: 441-83. PMID: 1525473
  2. 碱性磷酸酶和肿瘤抑制。  |  FLEMING, RF. and PECZENIK, O. 1948. Nature. 162: 338. PMID: 18934247
  3. 单个氨基酸的突变将生殖细胞碱性磷酸酶转化为胎盘碱性磷酸酶。  |  Watanabe, T., et al. 1991. J Biol Chem. 266: 21174-8. PMID: 1939159
  4. 心脏手术中用碱性磷酸酶进行预防性治疗可诱导内源性碱性磷酸酶释放。  |  Kats, S., et al. 2012. Int J Artif Organs. 35: 144-51. PMID: 22395920
  5. 干细胞中的碱性磷酸酶。  |  Štefková, K., et al. 2015. Stem Cells Int. 2015: 628368. PMID: 25767512
  6. 碱性磷酸酶和低磷酸酶。  |  Millán, JL. and Whyte, MP. 2016. Calcif Tissue Int. 98: 398-416. PMID: 26590809
  7. 碱性磷酸酶触发的同步水凝胶化和化学发光。  |  Hai, Z., et al. 2017. J Am Chem Soc. 139: 1041-1044. PMID: 28064496
  8. 用碱性磷酸酶脱磷酸化DNA片段。  |  Green, MR. and Sambrook, J. 2020. Cold Spring Harb Protoc. 2020: 100669. PMID: 32747587
  9. 骨质疏松症女性体内的碱性磷酸酶。  |  Hulth, AG., et al. 1979. Acta Med Scand. 206: 201-3. PMID: 495227
  10. 妊娠期的中性粒细胞碱性磷酸(酯)酶。  |  Beal, RW., et al. 1967. J Clin Pathol. 20: 749-51. PMID: 5602987

订购信息

产品名称产品编号规格价格数量收藏夹

Alkaline Phosphatase 抗体 (G-9)

sc-398461
200 µg/ml
RMB2377.00

Alkaline Phosphatase (G-9): m-IgG Fc BP-HRP 套装

sc-538448
200 µg Ab; 10 µg BP
RMB2662.00

Alkaline Phosphatase (G-9): m-IgGκ BP-HRP 套装

sc-536066
200 µg Ab; 40 µg BP
RMB2662.00

Alkaline Phosphatase (G-9): m-IgG1 BP-HRP 套装

sc-545707
200 µg Ab; 20 µg BP
RMB2662.00

What does low (25 IU/L) Alkaline Phosphatase indicate? 

Asked by: David G
IU stands for international unit per Liter. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2023-03-21

I need to use an antibody to detect the protein in samples of equine origin. Do you know if sc-398461: Alkaline Phosphatase (G-9) mouse monoclonal antibody will work?

Asked by: Trav11
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 5 out of 5 by from Produced positive Western blot data of PLAPProduced positive Western blot data of PLAP expression in non-transfected and human PLAP transfected 293T whole cell lysates and human placenta tissue extract . -SCBT QC
Date published: 2014-01-21
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Alkaline Phosphatase 抗体 (G-9) is rated 5.0 out of 5 by 1.
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