Date published: 2025-9-7

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Adducin α 抗体 (C-4): sc-133078

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说明书
  • Adducin α抗体(C-4)是小鼠单克隆IgG2a κ, 在1篇文献中引用,规格为200 µg/ml
  • 免疫human物种的Adducin α的氨基酸581-680
  • 推荐用于 mouse, rat 和 human 来源的Adducin α WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgG Fc BP-HRPm-IgG2a BP-HRP 是 Adducin α 抗体 (C-4) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Adducin α 抗体 (C-4) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

Adducin是由三个基因(α、β、γ)编码的细胞骨架蛋白家族。 Adducin是与质膜内叶相关的蛋白质,是位于膜骨架的收缩蛋白-肌动蛋白连接处的蛋白质之一。皮质肌动蛋白骨架网络在细胞凋亡过程中丢失,Adducin是皮质肌动蛋白网络组织的核心。 Adducinα是与肾小管钠泵活性相关的细胞骨架蛋白,与高血压有关。与Adducinβ的有限表达相反,Adducinα和Adducinγ的表达普遍存在。 Adducinβ在脑和造血组织中高水平表达,如人类骨髓和小鼠脾脏。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Adducin α 抗体 (C-4) 参考文献:

  1. 米兰高血压大鼠血压数量性状位点的遗传图谱。  |  Zagato, L., et al. 2000. Hypertension. 36: 734-9. PMID: 11082136
  2. 波兰高血压患者α-胰高血糖素基因的 Gly460Trp 多态性与血压的盐敏感性之间缺乏关联。  |  Ciechanowicz, A., et al. 2001. Kidney Blood Press Res. 24: 201-6. PMID: 11528213
  3. 小细胞肺癌 c-MET/HGF 通路的下游信号和特异性抑制:对肿瘤侵袭的影响。  |  Ma, PC., et al. 2007. Br J Cancer. 97: 368-77. PMID: 17667909
  4. 纯化与细胞-细胞粘附分子 E-cadherin(uvomorulin)密切相关的 92 kDa 细胞质蛋白。蛋白质复合物的特征和从细胞结构中提取的可能性。  |  McCrea, PD. and Gumbiner, BM. 1991. J Biol Chem. 266: 4514-20. PMID: 1999432
  5. Adducin是角质形成细胞脱膜粘合所必需的。  |  Rötzer, V., et al. 2014. J Biol Chem. 289: 14925-40. PMID: 24711455
  6. Adducin 家族基因多态性与高血压的流行病学证据综述。  |  Zhang, JR., et al. 2019. Cardiol Res Pract. 2019: 7135604. PMID: 31275642
  7. 肿瘤细胞中磷酸化 adducin 的表达增加。  |  Luo, C., et al. 2020. J Int Med Res. 48: 300060520910646. PMID: 32237935
  8. 一种γ-adducin裂解片段可诱导阿尔茨海默病的神经元缺陷和突触功能障碍。  |  Xiong, M., et al. 2021. Prog Neurobiol. 203: 102074. PMID: 33992672
  9. adducin传奇:人类高血压-血管、肾脏和认知疾病精准医疗的多效应基因组靶点。  |  Gonzalez-Fernandez, E., et al. 2022. Physiol Genomics. 54: 58-70. PMID: 34859687
  10. Adducin 在心肌细胞有丝分裂过程中调控肌节分解  |  Xiao, F., et al. 2024. Circulation. 150: 791-805. PMID: 38708635

订购信息

产品名称产品编号规格价格数量收藏夹

Adducin α 抗体 (C-4)

sc-133078
200 µg/ml
RMB2377.00

Adducin α (C-4): m-IgG Fc BP-HRP 套装

sc-539843
200 µg Ab; 10 µg BP
RMB2662.00

Adducin α (C-4): m-IgG2a BP-HRP 套装

sc-546795
200 µg Ab; 10 µg BP
RMB2662.00

Can Adducin α (C-4): sc-133078 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: TinTin
Thank you for your question. Yes, Adducin α (C-4): sc-133078 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-01
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Rated 5 out of 5 by from Very strong positive signal observed in WBVery strong positive signal observed in WB in T98G and H4 whole cell lysates. -SCBT QC
Date published: 2015-07-08
Rated 5 out of 5 by from Produced great immunoperoxidase cytoplasmicProduced great immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human colon tissue. -SCBT QC
Date published: 2015-04-01
Rated 5 out of 5 by from Light band observed in WB in 293T whole cellLight band observed in WB in 293T whole cell lysate. -SCBT QC
Date published: 2015-02-28
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Adducin α 抗体 (C-4) is rated 5.0 out of 5 by 3.
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