Date published: 2025-9-6

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Actin 抗体 (8.S2.1): sc-70319

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说明书
  • Actin抗体(8.S2.1)是小鼠单克隆IgM κ, 在53篇文献中引用,规格为200 µg/ml
  • 针对human来源的单核细胞和U-937组织溶解性淋巴瘤
  • 推荐用于 mouse, rat, human 和 rabbit 来源的Actin WB, IP, IF, IHC(P) 和 FCM检测; 与N-terminal 40 amino acids不交叉反应
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 beta Actin (C4): sc-47778,可查看有标记的 Actin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成Actin 抗体 (8.S2.1)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

肌动蛋白抗体(8.S2.1)是一种针对单核细胞和人源性U-937组织溶解性淋巴瘤的小鼠单克隆IgM kappa轻链抗体,可显示与小鼠、大鼠、人和兔的免疫反应。肌动蛋白在细胞骨架中形成微丝的过程中起着关键作用,它以球状(G-肌动蛋白)和丝状(F-肌动蛋白)两种形式存在,对于肌肉收缩、细胞运动以及维持细胞形状和完整性等各种细胞过程至关重要。肌动蛋白丝既可以形成稳定的结构(如肌肉肌节中的肌动蛋白丝),也可以形成动态结构(如运动细胞的前缘)。肌动蛋白主要存在于细胞质中,但也存在于细胞核中,有助于染色质重塑和基因转录。肌动蛋白的动态变化受小GTP酶(如Rho、Rac和Cdc42)的调节:Rho调节应力纤维和细胞黏附斑的形成;Rac控制肌动蛋白在细胞膜上的积聚,从而形成板状足;Cdc42则刺激丝状足的形成。肌动蛋白与多种蛋白质相互作用,包括肌动蛋白肌球蛋白(用于肌肉收缩)、原肌球蛋白和肌钙蛋白(用于肌肉调节)以及调节肌动蛋白聚合和解聚的蛋白(如微丝蛋白和微丝蛋白)。这些相互作用对于细胞运动、分裂和细胞内运输至关重要,凸显了肌动蛋白在维持细胞功能和结构方面的重要性。抗肌动蛋白抗体(8.S2.1)是研究肌动蛋白动力学和相关蛋白-蛋白相互作用的有用工具,适用于各种物种。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Actin 抗体 (8.S2.1)

sc-70319
200 µg/ml
RMB2377.00

Actin 抗体 (8.S2.1) FITC

sc-70319 FITC
200 µg/ml
RMB2482.00

Actin 抗体 (8.S2.1) PE

sc-70319 PE
200 µg/ml
RMB2580.00

Can Actin (8.S2.1): sc-70319 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: AbPolly
Thank you for your question. Yes, Actin (8.S2.1): sc-70319 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-01
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Rated 5 out of 5 by from 功能很出色我在一个月前购买了该公司的产品,抗体超级好用,该公司是一个值得信赖的一个大品牌,蛋白条带特别漂亮,一定会回购。
Date published: 2018-10-16
Rated 5 out of 5 by from Molto efficaceHo sempre usato questo anticorpo e devo dire che sono molto soddisfatta
Date published: 2018-07-27
Rated 5 out of 5 by from single specific bandsObserved single specific bands at 43kda. 1: 1000 diluted the antibody. Tried different types of sample,very satisfied result.
Date published: 2017-09-02
Rated 5 out of 5 by from loading controlThis is a loading control antibody ,it gave us good result for WB and IHC analyisis of different types of sample.We often use the 1:600 diluted the antibody,strong band at 43kda.
Date published: 2017-08-26
Rated 5 out of 5 by from Good reactivityGood reactivity for WB with our cell lines, HSC-3, HSC-4, Cal-27 and so on. the band is specific and strong.
Date published: 2016-12-06
Rated 5 out of 5 by from Actin antibody recommandationI command this Actin antibody as the useful antibody. This antibody can identify the actin specifically in our cell assays, the band in WB was strong.
Date published: 2016-11-24
Rated 4 out of 5 by from Good reactivity with both human and mouseGood reactivity with both human and mouse in Western. -SCBT QC
Date published: 2014-11-15
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Actin 抗体 (8.S2.1) is rated 4.9 out of 5 by 7.
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