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ABC1 Antibody (AB.H10) - Western Blotting - Image 108981
ABC1 抗体 (AB. H10): sc-58219. MES-SA/Dx5 全细胞裂解液中 ABC1 表达的 Western 印迹分析.
ABC1 Antibody (AB.H10) - Western Blotting - Image 108981
ABC1 抗体 (AB. H10): sc-58219. MES-SA/Dx5 全细胞裂解液中 ABC1 表达的 Western 印迹分析.
ABC1 Antibody (AB.H10) - Western Blotting - Image 394944
ABC1 抗体 (AB. H10): sc-58219. U-87 MG (A) 和 WI-38 (B) 全细胞裂解液中 ABC1 表达的 Western 印迹分析.
ABC1 抗体 (AB. H10): sc-58219. MES-SA/Dx5 全细胞裂解液中 ABC1 表达的 Western 印迹分析.

ABC1 抗体 (AB.H10): sc-58219

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说明书
  • ABC1 抗体 AB.H10 是小鼠单克隆 IgG1，ABC1抗体, 在48篇文献中引用，规格为100 µg/ml
  • 针对ABC1的1800-2260氨基酸human来源
  • 推荐用于 mouse, rat 和 human 来源的ABC1 WB, IP, IF 和 IHC(P)检测
  • 关于如何获取ABC1 (AB.H10): sc-58219的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP 和 m-IgG1 BP-HRP 是 ABC1 抗体 (AB.H10) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与ABC1 抗体 (AB.H10) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 ABC 抗体包括 ABCF1, ABCG2, ABCF2, ABCA6, ABCB9, ABCC13, ABCC11, ABCD3 和 ABCB5

ABC1抗体（AB.H10）是一种IgG1小鼠单克隆ABC1抗体（也称为ATP结合盒亚家族A成员1抗体、Tangier病抗体、TD抗体、胆固醇外排调节蛋白抗体、CERP抗体、ATP结合盒1抗体、ABC-1抗体、磷脂转运ATP酶ABCA1抗体、ATP结合盒转运蛋白1抗体、HDLDT1抗体或HPALP1抗体），它通过WB、IP、IF和IHC(P)检测小鼠、大鼠和人的ABC1蛋白。ABC1抗体（AB.H10）作为非偶联的抗ABC1抗体。ABC1（用于ATP结合盒转运蛋白1）是ATP结合盒蛋白家族的一个成员，该家族在生物膜上运输各种分子。ABC1包含两个特征性的ATP结合域和12个跨膜域，这些跨膜域形成一个通道样结构以便于运输。ABC1基因的突变与Tangier病有关，该病的特点是血清高密度脂蛋白水平较低。ABC1在人体组织中广泛表达，在肝脏、肺、肾上腺、胎盘和胎儿组织中的表达水平较高。ABC1的表达在单核细胞分化过程中被诱导，并在乙酰化低密度脂蛋白存在的情况下上调。ABC1可能在巨噬细胞脂质代谢和炎症中具有双重调节功能。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

ABC1 抗体 (AB.H10) 参考文献:

  1. 丹吉尔病是由编码 ATP 结合盒转运体 1 的基因突变引起的。  |  Rust, S., et al. 1999. Nat Genet. 22: 352-5. PMID: 10431238
  2. 人类 ATP 结合盒转运体 1 (ABC1)：基因组组织和丹吉尔病原种基因缺陷的鉴定。  |  Remaley, AT., et al. 1999. Proc Natl Acad Sci U S A. 96: 12685-90. PMID: 10535983
  3. 清道夫受体-BI 可抑制巨噬细胞中 ATP 结合盒转运体 1- 介导的胆固醇外流。  |  Chen, W., et al. 2000. J Biol Chem. 275: 30794-800. PMID: 10896940
  4. ABC1 基因产物的结构、功能和调控。  |  Schmitz, G. and Langmann, T. 2001. Curr Opin Lipidol. 12: 129-40. PMID: 11264984
  5. ATP 结合盒转运体 1 可减轻卵清蛋白诱发的中性粒细胞气道炎症。  |  Dai, C., et al. 2014. Am J Respir Cell Mol Biol. 51: 626-36. PMID: 24813055
  6. ATP 结合盒转运体 1（ABCA1）缺乏会降低血小板反应性，并减少血栓素 A2 的产生，而与造血 ABCA1 无关。  |  Lhermusier, T., et al. 2016. J Thromb Haemost. 14: 585-95. PMID: 26749169
  7. 恢复视网膜中 AIBP 的表达可为青光眼患者提供神经保护。  |  Ju, WK., et al. 2023. bioRxiv.. PMID: 37905114
  8. ABC 转运体促进 ATP 传导运输。  |  Schwiebert, EM. 1999. Am J Physiol. 276: C1-8. PMID: 9886914

订购信息

产品名称产品编号规格价格数量收藏夹

ABC1 抗体 (AB.H10)

sc-58219
100 µg/ml
RMB2377.00

ABC1 (AB.H10): m-IgG Fc BP-HRP 套装

sc-539078
100 µg Ab; 10 µg BP
RMB2662.00

ABC1 (AB.H10): m-IgG1 BP-HRP 套装

sc-541244
100 µg Ab; 20 µg BP
RMB2662.00

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: jerojero
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2018-06-14
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Rated 4 out of 5 by from buon funzionamento WBSoddisfatta della funzionalità dell'anticorpo, dil 1:500
Date published: 2025-05-30
Rated 4 out of 5 by from Easy to use!It has a pretty good outcome. Clear band and clean background.
Date published: 2018-01-30
Rated 5 out of 5 by from ABC1 strongABC1 antibody works with MES-SA/Dx5 cells for WB, very strong
Date published: 2017-05-20
Rated 5 out of 5 by from worked quite wellThat was the one I used it perfectly and the band I obtained sharp and accurate. Every experiment that i made was ended up happines with results
Date published: 2017-03-14
Rated 5 out of 5 by from Very popular!This mouse monoclonal ABC1 antibody, clone AB.H10, is a very popular choice for Western blot detection of mouse and human ABC1! It has been featured in over a dozen publications, 2 within the last year!
Date published: 2017-01-23
Rated 4 out of 5 by from Published data for WB in mouse macrophagePublished data for WB in mouse macrophage cell line J774A.1 (BCRC 60140).
Date published: 2015-05-16
Rated 4 out of 5 by from Published data for WB in pig Peripheral bloodPublished data for WB in pig Peripheral blood mononuclear cells. -SCBT Publication Review
Date published: 2015-05-14
Rated 4 out of 5 by from Published data for WB in human HepG2Published data for WB in human HepG2. -SCBT Publication Review
Date published: 2015-04-16
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ABC1 抗体 (AB.H10) is rated 4.3 out of 5 by 11.
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