[3H]- DCKA binding to NMDA receptor: IC50 = 0.13 µM (rat); Glutamate [NMDA] receptor subunit epsilon-3: IC50 = 0.13 µM (Xenopus oocytes); Binding towards Ionotropic glutamate receptor AMPA in presence of [3H]- AMPA: IC50 = 27 µM
Ki 数据 :
Affinity for the glycine binding site of NMDA receptor: Ki= 0.16 µM (rat); Displacement of [3H]AMPA from Ionotropic glutamate receptor AMPA: Ki= 1.64 µM