5-Amino-1,3,4-thiadiazole-2-sulfonamide (CAS 14949-00-9)

物理状态 :

Solid

溶解度 :

Soluble in DMSO, and methanol.

保存 :

Store at 4° C

熔点 :

188-190° C (dec.)

沸点 :

~484.2° C at 760 mmHg (Predicted)

密度 :

~1.9 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.68 (Predicted)

IC50 :

CA I: IC₅₀ = 2.6 µM (human); CA II: IC₅₀ = 2.9 µM (human)

Ki 数据 :

CA VII: K_i= 5.2 nM (human); CA XII: K_i= 33 nM (human); CA IX: K_i= 41 nM (human); Carbonic anhydrase 15: K_i= 48 nM (mouse); CA II: K_i= 60 nM (human)

pK值 :

pK_a: 7.76 (Predicted)

PubChem CID :

SMILES :

C1(=NN=C(S1)S(=O)(=O)N)N