Date published: 2025-9-7

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3BP2 抗体 (C-11): sc-377020

5.0(2)
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说明书
  • 3BP2抗体(C-11)是小鼠单克隆IgG2b κ, 在3篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的3BP2的N-terminus的氨基酸3-29之间
  • 推荐用于 mouse, rat 和 human 来源的3BP2 WB, IP, IF, IHC(P) 和 ELISA检测; 也和以下物种反应,包括: 和 canine and porcine
  • m-IgG2b BP-HRPm-IgGκ BP-HRP 是 3BP2 抗体 (C-11) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与3BP2 抗体 (C-11) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

3BP2是一种Syk家族激酶相互作用蛋白(SKIP),在脾脏和外周血白细胞中表达。3BP2最初被表征为Abl SH3相互作用蛋白,因为它含有一个富含脯氨酸的结构域和一个SH2结构域,与其他适配分子一致。在转染了3BP2的Jurkat T细胞中,T细胞受体(TCR)的刺激迅速诱导3BP2从细胞质向膜重新分布,在那里它与TCR蛋白酪氨酸激酶复合物结合。通过这种易位,3BP2能够选择性地与Flt3/Flk2受体以及磷酸化的Syk、LAT和ZAP-70蛋白结合。在T淋巴细胞中,3BP2的过表达,特别是SH2和富含脯氨酸结构域的过表达,足以诱导几种转录因子的激活,包括NFAT和AP-1。这种反式激活导致IL-2基因启动子的上调,并提示3BP2在介导T细胞信号传导中的作用。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

3BP2 抗体 (C-11)

sc-377020
200 µg/ml
RMB2377.00

3BP2 (C-11): m-IgGκ BP-HRP 套装

sc-535538
200 µg Ab; 40 µg BP
RMB2662.00

3BP2 (C-11): m-IgG2b BP-HRP 套装

sc-549447
200 µg Ab; 10 µg BP
RMB2662.00

3BP2 (C-11) 中和勝肽

sc-377020 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-377020 P appropriate for?

Asked by: Professor Griffin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-25
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Rated 5 out of 5 by from Exceptional immunoperoxidase cytoplasmicExceptional immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human upper stomach tissue. -SCBT QC
Date published: 2015-03-09
Rated 5 out of 5 by from Produced positive Western Blot data of 3BP2Produced positive Western Blot data of 3BP2 expression in non-transfected 293T, human 3BP2 transfected 293T and Jurkat whole cell lysates. -SCBT QC
Date published: 2013-04-06
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3BP2 抗体 (C-11) is rated 5.0 out of 5 by 2.
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