Date published: 2025-9-7

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2-Bromoaldisine (CAS 96562-96-8)

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备用名:
2-Bromo-6,7-dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione
应用:
2-Bromoaldisine 是 Raf/MEK-1/MAPK 级联的抑制剂
CAS号码:
96562-96-8
纯度:
≥96%
分子量:
243.1
分子式:
C8H7BrN2O2
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

快捷链接

2-Bromoaldisine 是 Raf/MEK-1/MAPK 级联的抑制剂(IC50= 539nM)。


2-Bromoaldisine (CAS 96562-96-8) 参考文献

Marine natural products: pyrrololactams from several sponges: F.J. Schmitz, et al.; J. Nat. Prod. 48, 47 (1985) Total syntheses of hymenialdisine and debromohymenialdisine: Stereospecific construction of the 2-amino-4-oxo-2-imidazolin-5(Z)-disubstituted y ylidene ring system: H. Annoura & T. Tatsuoka; THL 36, 413 (1995) Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1): D. Tasdemir, et al.; J. Med. Chem. 45, 529 (2002) Anti-Cancer Metabolites from Marine Sponges: D. Tasdemir; Biodiversity: Biomolecular Aspects of Biodiversity and Innovative Utilization 2002, 187 Synthesis and target identification of hymenialdisine analogs: Y. Wan, et al.; Chem. Biol. 11, 247 (2004) Novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella verrucosa: A. Aiello, et al.; Bioorg. Med. Chem. 14, 17 (2006) Stereoselective synthesis of (Z)-axino- and (Z)-debromoaxinohydantoin: F. Tutino, et al.; Tetrahedron 65, 2372 (2009)

订购信息

产品名称产品编号规格价格数量收藏夹

2-Bromoaldisine, 0.5 mg

sc-202880
0.5 mg
RMB869.00