Santa Cruz Biotechnology offers conjugated and unconjugated monoclonal primary antibodies directed against most tumor suppressors and proteins involved in apoptosis. Neoplastic growth arises from the dysregulation of cell growth, proliferation, and programmed death. Various tumor suppressors prevent such aberrant cell expansion by slowing progression of the cell cycle, or by inducing apoptosis. Deletions and mutations of tumor suppressors have been associated with cancer development. Select antibodies are listed within this chapter.
Most of our popular antibodies are also available as ImmunoCruz® Conjugates, including AC, HRP, PE, FITC, Alexa Fluor® 488, 546, 594, 647, 680, and 790 conjugates for direct Western Blotting and Staining applications, eliminating the need for a secondary antibody. Additional conjugates are also available for many antibodies, including Biotin, TRITC, PE-Cy5, PE-Cy7, APC, APC-Cy7, Alexa Fluor® 405, PerCP and PerCP-Cy5.5.