Small integral membrane protein 45, or SMIM45, is a protein that, as its name suggests, is an integral component of cellular membranes. The SMIM45 gene encodes this protein in humans. Integral membrane proteins like SMIM45 are essential for a variety of cellular functions due to their permanent residence within the lipid bilayer of cells.The designation of SMIM45 as a 'small' protein indicates that it may have a very specific and possibly niche role within the cell membrane. These roles can range from participating in the transport of molecules across the membrane to involvement in cell signaling pathways or contributing to the structural framework of the membrane.
Structurally, SMIM45 likely contains hydrophobic domains that allow it to anchor within the hydrophobic core of the lipid bilayer, while it may also present hydrophilic regions that interface with the aqueous environment inside and outside the cell. This arrangement facilitates SMIM45's ability to interact with a variety of molecular entities, from ions to larger biomolecules.The precise biological role of SMIM45 is not well-documented, which is common for many such membrane proteins. It may be involved in cellular processes like signal transduction, acting as a point of communication between the cell and its external environment, or in maintaining the structural integrity and fluidity of the membrane.Research into SMIM45 and its specific functions in the cell is necessary to fully understand the roles it plays. This research could include studies of its expression in different tissues, the conditions under which its expression is upregulated or downregulated, and potential protein-protein interactions within the membrane.
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产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
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Cholesterol | 57-88-5 | sc-202539C sc-202539E sc-202539A sc-202539B sc-202539D sc-202539 | 5 g 5 kg 100 g 250 g 1 kg 25 g | ¥293.00 ¥31071.00 ¥1422.00 ¥2324.00 ¥6453.00 ¥970.00 | 11 | |
胆固醇对细胞膜的结构和功能至关重要。它可以通过改变膜的流动性和微域组成来影响整体膜蛋白的功能。 | ||||||
L-α-Lecithin, Egg Yolk, Highly Purified | 8002-43-5 | sc-203096 | 250 mg | ¥880.00 | ||
这种磷脂对膜的完整性起着关键作用,可间接影响 SMIM45 等小型整体膜蛋白的功能。 | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | ¥1828.00 ¥3565.00 ¥6307.00 ¥10030.00 ¥19100.00 | 7 | |
S1P 参与调节迁移和存活等细胞过程的信号通路,可能对膜相关蛋白产生影响。 | ||||||
C2 Ceramide | 3102-57-6 | sc-201375 sc-201375A | 5 mg 25 mg | ¥869.00 ¥3565.00 | 12 | |
神经酰胺参与细胞信号传导并影响膜结构,可能会影响膜蛋白的活性。 | ||||||
FTY720 | 162359-56-0 | sc-202161 sc-202161A sc-202161B | 1 mg 5 mg 25 mg | ¥361.00 ¥846.00 ¥1331.00 | 14 | |
这种鞘氨醇类似物可调节鞘氨醇-1-磷酸受体的信号传导,从而可能影响膜蛋白的功能。 | ||||||
Ezetimibe | 163222-33-1 | sc-205690 sc-205690A | 25 mg 100 mg | ¥1061.00 ¥2663.00 | 12 | |
依折麦布以肠道细胞中的 Niemann-Pick C1-like 1 蛋白为靶细胞,影响胆固醇的吸收,并可能影响其他小的整体膜蛋白。 | ||||||
U 18666A | 3039-71-2 | sc-203306 sc-203306A | 10 mg 50 mg | ¥1579.00 ¥5641.00 | 2 | |
这种制剂会破坏胆固醇的运输,可用于研究膜成分的改变对整体膜蛋白的影响。 | ||||||
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | ¥417.00 ¥869.00 ¥2076.00 ¥5754.00 ¥13809.00 ¥65594.00 | 8 | |
尼古丁酰胺会破坏各种细胞信号通路,并可能间接影响 SMIM45 等蛋白质的功能。 | ||||||
Progesterone | 57-83-0 | sc-296138A sc-296138 sc-296138B | 1 g 5 g 50 g | ¥226.00 ¥575.00 ¥3294.00 | 3 | |
黄体酮与膜结合受体相互作用,并可能间接影响其他小型整体膜蛋白。 | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | ¥338.00 ¥982.00 ¥1489.00 ¥4896.00 | 13 | |
作为一种降低胆固醇的药物,辛伐他汀可能会改变膜的组成,并可能影响膜蛋白的活性。 |