KLH is a large, multi-subunit, oxygen-carrying protein found in the hemolymph of the marine gastropod, the Keyhole Limpet (genus Megathura).Hemocyanins, including KLH, are copper-containing proteins that bind and transport oxygen in many mollusks and arthropods. They're notable for their blue color when oxygenated. KLH, in particular, is of significant interest to biomedical research and development due to its strong immunogenic properties.KLH is composed of two distinct subunits known as KLH1 and KLH2, which are assembled into large, cylindrical structures. Each subunit is built from multiple copies of a ~350 kDa protein, which associate to form the decameric subunits. These can then aggregate into didecamers or multidecamers to form the functional hemocyanin.
The KLH protein is often used as a carrier protein in vaccine development because it can stimulate the immune system and enhance the body's response to an associated antigen. However, the specific structure and immunogenic properties can vary between KLH1 and KLH2.If "Keyhole Limpet Hemocyanin A" refers to a specific subunit or variant of KLH, I recommend checking the latest research or reaching out to experts in the field for more information. It's also important to note that ethical considerations should be taken into account when using KLH, as the Keyhole Limpet is a non-domesticated species collected from the wild.
产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
---|---|---|---|---|---|---|
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | ¥1568.00 ¥7334.00 | 2 | |
双链 RNA 的合成类似物,在包括 KLH 在内的疫苗制剂中用作免疫刺激剂。 | ||||||
Squalene | 111-02-4 | sc-281155 sc-281155A sc-281155B | 10 ml 100 ml 500 ml | ¥542.00 ¥1015.00 ¥2381.00 | 1 | |
一种有机化合物,用于某些佐剂配方,以增强疫苗中 KLH 的免疫反应。 | ||||||
Chitosan | 9012-76-4 | sc-221421 sc-221421A sc-221421B sc-221421D sc-221421C | 10 g 25 g 100 g 8 kg 500 g | ¥451.00 ¥609.00 ¥1489.00 ¥36937.00 ¥3294.00 | 6 | |
用作疫苗配方中的递送系统,有可能增强对 KLH 的免疫反应。 | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | ¥745.00 ¥3136.00 | 6 | |
在基于 KLH 的疫苗配方中,可以使用 Toll 样受体激动剂来刺激免疫系统。 | ||||||
GM-CSF | 83869-56-1 | sc-280759 | 5 µg | ¥5822.00 | 1 | |
有时用作佐剂,以增强疫苗中对 KLH 的免疫反应。 |