HIP1 抑制因子
HIP1 (Huntingtin Interacting Protein 1) inhibitors refer to a group of chemical compounds that are known to interact with and modulate the activity of the HIP1 protein. HIP1 is involved in various cellular processes, including endocytosis, vesicular trafficking, and receptor internalization. Inhibitors of HIP1 may have applications in research to study the function of HIP1 and its role in cellular processes.
Some compounds, such as HTI-286 (Hemiasterlin), Quercetin, EHop-016, Quinacrine, Hip1R, Pitstop 2, and Dynasore, have been reported to inhibit HIP1-mediated endocytosis or interfere with its binding to microtubules. Other compounds, like Eribulin, VD-168, In-2, TAT-HIP1, and IWP-2, have also been investigated for their inhibitory effects on HIP1.
| 产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
|---|---|---|---|---|---|---|
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | ¥124.00 ¥192.00 ¥1218.00 ¥2764.00 ¥10357.00 ¥553.00 | 33 | |
通过与其催化位点直接相互作用，阻止底物结合，从而阻断 Hip 的活性。 | ||||||
EHop-016 | 1380432-32-5 | sc-497382 | 5 mg | ¥880.00 | ||
通过破坏 Hip 的二聚化来抑制 Hip，这对其酶功能至关重要。 | ||||||
Pitstop 2 | 1419093-54-1 | sc-507418 | 10 mg | ¥4062.00 | ||
通过与 Hip 的异构位点竞争性结合，阻止底物进入，从而抑制 Hip。 | ||||||
Glasdegib | 1095173-27-5 | sc-507353 | 5 mg | ¥1862.00 | ||
通过特异性抑制对酶活性至关重要的 ATP 结合域来抑制 Hip 的活性。 | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | ¥982.00 | 44 | |
通过破坏激活髋关节所必需的内细胞途径，阻断髋关节的功能。 | ||||||
Eribulin | 253128-41-5 | sc-507547 | 5 mg | ¥9759.00 | ||
通过破坏髋关节与激活髋关节所需的辅助因子的相互作用，抑制髋关节的功能。 | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | ¥1061.00 ¥3227.00 | 27 | |
通过破坏髋关节与激活髋关节所必需的调节蛋白的相互作用来抑制髋关节的功能。 | ||||||