Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Werner's syndrome (WS), also called adult progeria, is an inherited, autosomal recessive disorder that is most common in families from regions of Japan where consanguineous marriages occur frequently. WS is characterized by premature aging and the early onset of age-related diseases and commonly results in cancer. The gene responsible for Werner's syndrome, WRN, has been mapped to the short arm of chromosome 8, and the subsequent cloning of the gene has reveled a predicted protein of 1,432 amino acids in length that bears significant sequence homology with DNA helicases. Four mutations in WRN have been identified in patients afflicted with WS. Two of the mutations involve mRNA splice-junctions. Of these two mutations, one was found in 60% of the individuals examined. This mutation is predicted to cause a frameshift which results in a truncated WRN protein.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.