Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). UBC12, also known as UBE2M (ubiquitin-conjugating enzyme E2M), hUbc12 or UBC-RS2, is a 183 amino acid member of the E2 ubiquitin-conjugating enzyme family. UBC12 is linked with NEDD8 (neural precursor cell expressed, developmentally down-regulated 8), a ubiquitin-like protein. Via this interaction, UBC12 facilitates the attachment of NEDD8 to proteins targeted for degradation. Due to its ability to control the conjugation of NEDD8 to cellular proteins, UBC12 is thought to play a role in cell proliferation events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
I am using UBC12 (L-34): sc-100608 for immunofluorescence, what dilution of this antibody should I use?
Asked by: jerojero
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: