Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TXNDC4 (thioredoxin domain containing 4), also known as ERP44, is a 406 amino acid protein that contains one thioredoxin domain, a motif that participates in various redox reactions throughout the cell. Localized to the lumen of the endoplasmic reticulum (ER), TXNDC4 functions to inhibit the activity of IP3R-I (inositol 1,4,5-triphosphate receptor,type 1) within calcium channels. In addition, TXNDC4 is thought to regulate oxidative protein folding within the ER and may be involved in retaining proteins, such as Ero1-Lβ and Ero1-Lα, in the ER. TXNDC4 expression is induced by ER stress, further suggesting an important role for TXNDC4 in the maintenance of intraluminal conditions. TXNDC4 contains an N-terminal ER targeting sequence, as well as a C-terminal ER retention signal (RDEL), both of which keep TXNDC4 within the ER.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-100600: TXNDC4 (Y-19) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: jerojero
Thank you for your question. Yes, sc-100600: TXNDC4 (Y-19) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: