Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Tom34 Antibody (S-05) is a high quality monoclonal Tom34 antibody (also designated TOMM34 antibody) suitable for the detection of the Tom34 protein of human origin. Tom34 Antibody (S-05) is available as the non-conjugated anti-Tom34 antibody. The mitochondrial preprotein translocases of the outer membrane (Tom) form a multisubunit complex that facilitates the import of nuclear-encoded precursor proteins across the mitochondrial outer membrane. The Tom machinery consists of import receptors for the initial binding of cytosolically synthesized preproteins, and a general import pore (GIP) for the membrane translocation of various preproteins into the mitochondrion. Tom34 (translocase of outer mitochondrial membrane 34), also known as TOMM34, URCC3 or HTOM34P, is a ubiquitously expressed 309 amino acid protein that contains six TPR repeats. Localized to the cytoplasmic side of the mitochondrion, Tom34 functions as a chaperone-like protein that binds the mature portion of unfolded proteins and guides their import into mitochondria. In addition, Tom34 is thought to have weak ATPase activity and may interact with other organelles within the cell. Expression of Tom34 is upregulated in colon cancer cells and is thought to be involved in tumor progression. Tom34 may, therefore, be a novel target for therapeutic anti-cancer drugs.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Is the anti TOMM34 antibody sc-101284 also suitable to detect mouse TOM34?
Asked by: Edding400
Thank you for your question. This antibody has not yet been tested in mouse and so that is not a recommended species at this time. We are still gathering data to show on our website. Check back for updates!
Answered by: Tech Service
Date published: 2019-06-11
I am using Tom34 (S-05): sc-101284 for immunofluorescence, what dilution of this antibody should I use?
Asked by: Germaine
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: