Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TGase3 Antibody (H3) is a high quality monoclonal TGase3 antibody (also designated Transglutaminase-3 antibody, TGM3 antibody or TGE antibody) suitable for the detection of the TGase3 protein of human origin. TGase3 Antibody (H3) is available as the non-conjugated anti-TGase3 antibody. TGases (transglutaminases) catalyze the post-translational modification of proteins by transamidation of available glutamine residues, resulting in a stable, insoluble macromolecular structure. The human haploid genome contains at least five distinct transglutaminases that are differentially expressed in time-space and tissue-specific ways. Epidermal-type TGase (TGase3), also known as TGE, TGX and TGM3, is involved in the formation of the cornified cell envelope by cross-linking a variety of structural proteins in the epidermis. It is expressed during late stages of terminal differentiation of the epidermis and in certain cell types of the hair follicle. TGase3 is widely expressed and is important for epithelial barrier formation. It is a zymogen, requiring proteolysis for activity. TGase3 is devoid of GTPase activity, but its TGase activity is inhibited by GTP as in the case of tissue-type TGase (TGase2). The gene encoding TGase3 maps to human chromosome 20q11.2.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-101366: TGase3 (H3) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: Germaine
Thank you for your question. Yes, sc-101366: TGase3 (H3) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: