TEX13A 抗体 (A-13): sc-100945

TEX13A (Testis-expressed sequence 13A) is a 409 amino acid protein that is expressed specifically in the testis. One of two human orthologs of the mouse Tex13 protein, TEX13A contains one RanBP2-type zinc finger domain; a motif that is thought to be involved in nucleocytoplasmic transport. Like its mouse counterpart, the gene encoding TEX13A is located on chromosome X, suggesting a possible role in the pre-meiotic stages of mammalian spermatogenesis. Translocations in the chromosomal region in which the TEX13A gene is located may be involved in the pathogenesis of azoospermia, a condition characterized by a complete absence of sperm in male semen. Chromosome X contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.