Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
SUR-1 Antibody (3G5) is a high quality monoclonal SUR-1 antibody (also designated ATP binding cassette subfamily C member 8 antibody, SUR1 antibody or ABCC8 antibody) suitable for the detection of the SUR-1 protein of human origin. SUR-1 Antibody (3G5) is available as the non-conjugated anti-SUR-1 antibody. Both suphonylurea receptor-1 (SUR-1) and sulphonylurea receptor-2 (SUR-2) belong to the ATP-binding cassette superfamily associated with Kir 6.x. SUR-1 and Kir 6.x proteins are required for the regulation of glucose-induced insulin secretion by controlling K-ATP channel activity of the pancreatic beta-cell membrane while SUR-2 and Kir 6.x proteins reconstitute the cardiac and the vascular-smooth-muscle-type K-ATP channels. Loss-of-function mutations in the SUR-1 gene causes the disease Persistent Hyperinsulinemic Hypoglycemia of Infancy (PHHI). PHHI is characterized by increased irregular insulin secretion, which causes disorganized formation of new islets and leads to hypoglycemia, coma, and severe brain damage. The K-ATP channels controlled by SUR-2 are activated during myocardial ischemia, which suggests that mutations in the SUR-2 gene may cause channel malfunction and ischemic injury to the heart. No disease has yet been found to be associated with the SUR-2 gene.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.