Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
STC1 Antibody (1A3) is a high quality monoclonal STC1 antibody (also designated STC antibody, or Stanniocalcin-1 antibody) suitable for the detection of the STC1 protein of mouse, rat and human origin. STC1 Antibody (1A3) is available as the non-conjugated anti-STC1 antibody. Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are mammalian peptide hormones that were previously considered to be present only in bony fish, where they are involved in calcium homeostasis. STC1 plays a role in calcium and phosphate homoeostasis and is phosphorylated in vitro by protein kinase C, and STC2 is phosphorylated in vitro by casein kinase II (CK2). A human fibrosarcoma cell line, HT1080, expresses both STC1 and STC2 as secreted phosphoproteins in vivo, with STC2 being phosphorylated by an ecto-CK2-like enzyme. STC1 and STC2 have opposite effects on calcium and phosphate homeostasis, namely anti-hypercalcemic and anti-hypocalcemic actions, respectively. STC1 and STC2 are detected in human adrenal tumors, such as pheochromocytoma, differentiated neuroblastoma aldosterone-producing adenoma, and in cultured adrenal tumor cells (rat pheochromocytoma PC-12 cells and human neuroblastoma NB-1 cells).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Is this antibody suitable for immunohistochemistry staining？
Asked by: Fanng
Thank you for your question. Anti-STC1 Antibody (1A3): sc-293435 is recommended for detection of STC1 of mouse, rat and human origin by WB, IP, IF and ELISA.
It is not recommended for immunohistochemistry.
Answered by: Tech Support Europe
Date published: 2021-11-22
What is the recommended fixation method for immunofluorescence staining with STC1 (1A3): sc-293435 monoclonal antibody?
Asked by: Dr Ninau Qelp
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: