Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Replication-dependent histone mRNAs lack polyadenylated tails and instead end in a conserved stem-loop. The stem-loop binding protein (SLBP) binds the 3' end of histone mRNA and contains a 73 amino acid RNA-binding domain. SLBP mediates the interaction of the histone pre-mRNA with U7 SnRNP to facilitate 3' end processing. SLBP is required for the translation of stem-loop mRNAs. SLBP forms a stable complex with U7 SnRNP in the nucleus as well as the cytoplasm. hZFP100 is a zinc finger protein that interacts with the SLBP/RNA complex but not with free SLBP. During the cell cycle, SLBP increases in the late G1 and decreases in the S/G2 border. The regulation of SLBP occurs at the level of translation. Specifically, two phosphorylation events on threonine 99 and threonine 104 trigger the degradation of SLBP in late S phase cells.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
I am using SLBP (XX-3): sc-101140 for immunofluorescence, what dilution of this antibody should I use?
Asked by: jenni
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: