Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
SH3D19 (SH3 domain-containing protein 19), also known as EBP, EEN-binding protein, EVE1 or Kryn, is a 790 amino acid protein that is widely expressed with highest expression in kidney, heart, lung, liver, skeletal muscle and small intestine. Localized to the cytoplasm and recruited to the nucleus by a fusion protein known as MLL-EEN (mixed-lineage leukemia-endophilin), SH3D19 is thought to play a role in regulating the involvement of ADAM (A disintegrin and metalloproteases) proteins in EGFR (epidermal growth factor receptor)-ligand shedding pathways. SH3D19 contains five SH3 domains and may also function to suppress both Ras-induced cellular transformation and Ras-associated activation of proteins such as Elk-1. Translocation events involving the SH3D19 gene are implicated in acute myeloid leukemia, suggesting a possible role for SH3D19 in carcinogenesis. Five isoforms of SH3D19 are expres-sed due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.