m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for RUNX3 Antibody (R3-5G4) for WB and IHC(P) applications. This reagent is now offered in a bundle with RUNX3 Antibody (R3-5G4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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RUNX3 Antibody (R3-5G4) is a high quality monoclonal RUNX3 antibody (also designated CBFA3 antibody, AML2 antibody or PEBP2A3 antibody) suitable for the detection of the RUNX3 protein of human origin. RUNX3 Antibody (R3-5G4) is available as both the non-conjugated anti-RUNX3 antibody form, as well as multiple conjugated forms of anti-RUNX3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The mammalian Runt-related transcription factor (RUNX) family comprises three members, RUNX1 (also designated AML-1, PEBP2αB, CBFA2), RUNX2 (also designated AML-3, PEBP2αA, CBFA1, Osf2) and RUNX3 (also designated AML-2, PEBPαC, CBFA3), and belongs to the acute myeloid leukemia (AML) family. RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX3 is expressed in cells of hematopoietic origin, including myeloid and B-cell lines and spleen. By playing a role in controlling the growth and differentiation of gastric epithelial cells, RUNX3 is a strong candidate as a gastric cancer tumor suppressor. Specifically, hypermethylation inactivates the gene encoding RUNX3. The detection of hypermethylation at multiple regions within the RUNX3 CpG island may aid in the diagnosis and risk assessment of gastric cancer.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Hallo, ich würde gerne ein 10 µg GRATIS Sample vom RUNX3 (R3-5G4): sc-101553 erhalten. Ist das möglich?
MfG, Anja Nitzsche
Asked by: Anja Nitzsche
Sehr geehrte Frau Nitzsche,
vielen Dank für Ihre Anfrage. Wir freuen uns wenn Sie unsere Samples testen möchten. Dazu brauchen wir Ihre Adresse sowie Telefonnummer. Bitte schreiben Sie uns ihre Kontaktdaten an [email protected] oder rufen uns an unter der Telefonnummer: 06221 4503 0.
Answered by: Technical Support Europe
Date published: 2017-08-29
I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with RUNX3 (R3-5G4): sc-101553 monoclonal antibody?
Asked by: jenni
We recommend using one of our our exclusive Mouse IgG Binding Proteins (m-IgGκ) conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems.
A complete list of available binding proteins is available on our website here: