Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
RUFY1 (RUN and FYVE domain containing 1), also known as RABIP4 or ZFYVE12, is a 708 amino acid protein that localizes to the cytoplasm and the early endosome membrane. Highly expressed in testis, lung, brain and kidney, RUFY1 functions to bind phosphatidylinositol 3-phosphate-containing phospholipid vesicles and, via this interaction, participates in early endosomal trafficking. RUFY1 contains one RUN domain and one FYVE-type zinc finger through which it mediates its ability to bind phosphatidylinositol 3-phosphate. Upon DNA damage, RUFY1 may be phosphorylated by ATM or ATR. Additionally, the phosphorylation of Tyr 389 and/or Tyr 400 residues on human RUFY1 is thought to be necessary for endosomal localization. Three isoforms of RUFY1 exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.