Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF181 (RING finger protein 181) is a 153 amino acid protein that contains one RING-type zinc finger and belongs to the RNF181 family. RNF181 is auto-ubiquitinated as part of the enzymatic reaction, and upon DNA damage, RNF181 is phosphorylated by ATM or ATR. RNF181 demonstrates highest levels of expression in liver and heart, moderate levels in placenta, lung, liver, kidney, pancreas, and lower levels in brain and skeletal muscle. The RNF181 gene is conserved in chimpanzee, canine, bovine, mouse, rat, zebrafish and fruit fly, and maps to human chromosome 2p11.2.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
For Western Blot, is it recommended to use denatured or non-denatured conditions with RNF181 (F-9E): sc-101120 antibody?
Asked by: Professor Griffin
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.