Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. RIP4, also known as RIPK4 (receptor-interacting serine/threonine-protein kinase 4), PKK (PKC δ-interacting protein kinase), DIK, ANKK2 or ANKRD3 (ankyrin repeat domain-containing protein 3), is a peripheral membrane protein that belongs to the TKL Ser/Thr protein kinase family and functions as a receptor-interacting protein (RIP) that modulates epidermal growth and differentiation. RIPs interact with the intracellular domain of tumor necrosis factor receptors (TNFRs) and facilitate downstream signaling and apoptosis induction. RIP4 contains ten ankyrin-repeats and one protein kinase domain, and participates in the activation of NFκB. Two isoforms exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
For Western Blot, is it recommended to use denatured or non-denatured conditions with RIP4 (387.1): sc-100428 antibody?
Asked by: Dr Ninau Qelp
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.