Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
RING1B Antibody (N-32) is a high quality monoclonal RING1B antibody (also designated RING1B antibody) suitable for the detection of the RING1B protein of mouse, rat and human origin. RING1B Antibody (N-32) is available as the non-conjugated anti-RING1B antibody. Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. RING1B (E3 ubiquitin-protein ligase RING2), also known as RING2, RING finger protein BAP-1, DinG protein or HIP2-interacting protein 3, is a PcG protein involved in protein degradation and ubiquitination pathways. As an E3 ubiquitin-protein ligase that mediates monoubiquination of Histone H2A, RING1B is an essential component of the chromatin-associated class II PcG repressive complex 1 (PRC1/hPRC-H), a complex that represses transcription of many genes throughout development. RING1B contains one RING-type zinc finger domain that interacts with Huntington interacting protein 2 (HIP2) within the PRC1 complex during E3 ubiquitin ligase activity. Subcellularly located in the nucleus, RING1B may be involved in random and imprinted inactivation of the X chromosome in female mammals. Underexpression of RING1B in mice cause axial skeletal abnormalities and reduced expression of some HOX genes, while mice completely lacking RING1B exhibit gastrulation arrest.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.