Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
RGS3 Antibody (CC-Q7) is a high quality monoclonal RGS3 antibody (also designated RGS3 antibody) suitable for the detection of the RGS3 protein of human origin. RGS3 Antibody (CC-Q7) is available as the non-conjugated anti-RGS3 antibody. Heterotrimeric G proteins function to relay information from cell surface receptors to various intracellular effectors. G proteins comprise a, b and g subunits, and following activation, the a subunit binds GTP and dissociates from the bg complex. A large group of proteins have been identified as GTPase-activating proteins (GAPs), including the RGS (regulator of G protein signaling) family, which serve to deactivate specific Ga isoforms by increasing the rate at which they convert GTP to GDP. RGS3 is a protein of the RGS family that preferentially binds to the activated form of Ga11. Through this association, RGS3 inhibits Ga11-induced signaling, leading to a decrease in the accumulation of intracellular calcium and the inhibition of MAP kinase phosphorylation. RGS3 is highly expressed in adult kidney and myocardium, and it is primarily localized to the cytoplasm. Upon activation of Ga11, RGS3 translocates from the cytosol to the plasma membrane, thereby bringing RGS3 within close proximity to the targeted G protein.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.