Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
RDHE2 Antibody (36-N) is a high quality monoclonal RDHE2 antibody (also designated RDHE2 antibody) suitable for the detection of the RDHE2 protein of mouse, rat and human origin. RDHE2 Antibody (36-N) is available as the non-conjugated anti-RDHE2 antibody. RDHE2 (epidermal retinal dehydrogenase 2), also known as EPHD-2 or retSDR2 (retinal short chain dehydrogenase reductase 2), is a member of the short-chain dehydrogenase/reductase (SDR) family of enzymes that catalyze the first step in the generation of retinaldehyde from retinol. Expressed ubiquitously at low levels with predominant expression in fetal and adult lung, fetal kidney and fetal skin, RDHE2 localizes to the membrane and is a multi-pass membrane protein. RDHE2 contains three motifs that are conserved in most of the SDR family members: a TGXXXGXG motif, a YXXXK motif (the active-site) and an LXNNAG motif. This implies that, similar to other SDR family members, RDHE2 may be involved in the retinol metabolism pathway. In addition, RDHE2 may play a role in the pathogenesis of psoriasis vulgaris, a chronic inflammatory skin disease. This is suggested by the significant upregulation of RDHE2 mRNA levels in the affected skin of psoriasis patients.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
For Western Blot, is it recommended to use denatured or non-denatured conditions with RDHE2 (36-N): sc-100591 antibody?
Asked by: jenni
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.