RBMXL2 抗体 (RR-17): sc-101134

RBMXL2 Antibody (RR-17) is an IgG₁ κ mouse monoclonal RBMXL2 antibody (also designated RBMXL2 antibody) that detects the RBMXL2 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. RBMXL2 Antibody (RR-17) is available as the non-conjugated anti-RBMXL2 antibody. Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription and pre-mRNA processing, as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm. RBMXL2 (RNA binding motif protein, X-linked-like 2), also known as hnRPGT (heterogeneous nuclear ribonucleoprotein G T) or hnRNP G-T, is a testis-specific hnRNP that is predominantly expressed in meiotic spermatocytes. Localizing to the nucleus, RBMXL2 contains one RNA recognition motif (RRM) and may replace the function of hnRP G, acting as a germ cell-specific splicing regulator. Due to its specific function in spermatocytes, RBMXL2 is implicated in autosomal male infertility.

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References:

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