RACK7 抗体 (RF-9): sc-100824

RACK7 Antibody (RF-9) is an IgG₁ κ mouse monoclonal RACK7 antibody (also designated ZMYND8 antibody) suitable for the detection of the RACK7 protein of human origin by WB, IP and ELISA. RACK7 Antibody (RF-9) is available as the non-conjugated anti-RACK7 antibody. Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. Receptor for activated C kinases, termed RACKs, are intracellular receptors for activated PKC that serve as anchors and may be involved in the activation-induced translocation of PKC. RACK7 (receptor for activated C kinase 7), also known as ZMYND8 (zinc finger MYND domain-containing protein 8), PRKCBP1 (protein kinase C (PKC)-binding protein 1) or PRO2893, is a widely expressed protein with predominant expression in pancreas, lung, placenta and brain. RACK7 contains one bromodomain, one PHD-type zinc finger, one MYND-type zinc finger and one PWWP domain. Via its C-terminus, RACK7 interacts with PKC β and is believed to play a role in PKC signaling and function as a transcription regulator. In response to DNA damage, RACK7 is phosphorylated by ATM or ATR. In addition, multiple isoforms exist for RACK7.

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References:

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