Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Molecular chaperones are proteins that assist in the correct folding of other proteins in the crowded molecular environment that exists in living cells. Within this class of proteins, a key role is played by chaperonins, multisubunit toroidal (i.e. doughnut-shaped) assemblies that undergo major ATP-dependent conformational changes as part of the mechanism of facilitated folding. Prefoldin is a heterohexameric chaperone protein which has the ability to capture unfolded Actin. Six prefoldin polypeptides, prefoldin 1-6, have been identified. Prefoldin 1 is a 122 amino acid protein that binds specifically to cytosolic chaperonin (c-cpn) and transfers target proteins to it. Prefoldin 3 (VBP1 or VHL binding protein-1) forms complexes with VHL and is translocated from perinuclear granules to the nucleus or cytoplasm. Prefoldin 4 is a possible transcription factor. Prefoldin 5 (c-Myc-binding protein Mm-1, Myc modulator 1 or MM-1) is a c-Myc binding protein.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-100816: prefoldin 3 (YY-3Q) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: jenni
Thank you for your question. Yes, sc-100816: prefoldin 3 (YY-3Q) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here:
Rated 4 out of
Produced wonderful immunoperoxidase cytoplasmicProduced wonderful immunoperoxidase cytoplasmic staining in formalin-fixed, paraffin-embedded human breast cancer tissue. -SCBT QC