Pol II RPB5 抗体 (3Y11): sc-101605

Pol II RPB5 Antibody (3Y11) is an IgG1 mouse monoclonal Pol II RPB5 antibody that detects Pol II RPB5 of yeast origin by WB. Pol II RPB5 Antibody (3Y11) is available as the non-conjugated anti-Pol II RPB5 antibody form. Eukaryotes produce three distinct classes of RNA polymerase, designated Pol I, Pol II and Pol III. Each polymerase is responsible for the synthesis of a different class of RNA. Pol I transcribes rRNA (ribosomal RNA) genes, while Pol II transcribes protein-encoding genes into mRNA (messenger RNA) and Pol III transcribes the 5S rRNA genes and all of the tRNA (transfer RNA) genes. POLR2E (polymerase (RNA) II (DNA directed) polypeptide E, 25kDa), also known as RPB5, is a 210 amino acid nuclear protein that functions as the fifth largest subunit of Pol II and plays a role in transcription. The yeast homolog of POLR2E is known as Pol II RPB5 and, like its mammalian counterpart, exists as a component of Pol II and participates in the initiation and regulation of transcription.

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References:

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