Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US, Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxesShips via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal health products, bulky and/or heavy items
PIP5KIII Antibody (64-Q6) is a high quality monoclonal PIP5KIII antibody (also designated PIP5KIII antibody) suitable for the detection of the PIP5KIII protein of mouse, rat and human origin. PIP5KIII Antibody (64-Q6) is available as the non-conjugated anti-PIP5KIII antibody. Phosphorylation of phosphatidylinositol (PtdIns) derivatives is suggested to play a role in regulating cytoskeletal functions, membrane trafficking and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. PtdIns proteins are distinguished by the degree and position of phosphorylation of the inositol ring. PIP5KIII (Phosphatidylinositol 3-phosphate 5-kinase), also known as PIP5K3, FAB1, CFD, PIKFYVE or ZFYVE29 is 2,098 amino acid protein that synthesizes phosphatidylinositol-3,5-bisphosphate by catalyzing the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the inositol ring. PIP5KIII is thought to play a major role in nuclear migration and the endocytic-vacuolar pathway. PIP5KIII exists as four alternatively spliced isoforms and contains a DEP domain, a FYVE-type zinc finger and a PIPK domain. Defects in the gene encoding PIP5KIII lead to corneal fleck dystrophy (CFD), an autosomal disorder in which small white flecks are found throughout the corneal stroma..
种属 | 基因名称 | 基因ID | 染色质位置 | 亚型(mRNA)即位号码 | 蛋白质即位号码 | OMIM™ 号码 |
---|---|---|---|---|---|---|
Human | PIKFYVE | 200576 | 2q34 | XM_011510778, XM_011510779, XM_011510780, XM_011510781, XM_011510782, XM_011510783, XM_011510784, XM_011510785, XM_011510786, XM_011510787, XM_011510788, XM_011510789, XM_011510790, XM_011510792, XM_017003568, XM_017003569, XM_017003570, XM_017003571, XM_017003572, XM_017003573, XM_017003574, NM_001178000, NM_015040, NM_152671, NM_001002881 | Q9Y2I7 | 609414 |
Mouse | Pikfyve | 18711 | 1 C2 | XM_006495776, XM_006495777, XM_006495779, XM_006495781, XM_006495782, XM_011238454, NM_001310624, NM_011086 | Q9Z1T6 | N/A |