Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
PILR-α Antibody (47-12) is a high quality monoclonal PILR-alpha antibody (also designated PILR-α antibody) suitable for the detection of the PILR-alpha protein of human origin. PILR-α Antibody (47-12) is available as the non-conjugated anti-PILR-alpha antibody. PILR-α (paired immunoglobulin (Ig)-like type 2 receptor α), also known as FDF03, is a member of the paired Ig-like type 2 receptor family and is predominantly expressed in hemopoietic tissues but is also found in macrophages, monocytes, granulocytes and dendritic cells. Typically consisting of two highly related but functionally opposite (inhibiting and activating) receptors, paired receptors play an important role in the regulation of the immune system and in the recognition of the sialylated O-glycosylated ligand MIC2. PILR-α is the inhibitory component of the paired Ig-like type 2 receptor and PILR-β is the activating component. PILR-α contains an immune receptor tyrosine-based inhibitory motif (ITIM) which mediates the recruitment of a phosphatase for the inhibition of immune responses. Due to alternative splicing events, four isoforms exist for PILR-α. Isoforms 1 and 2 are single-pass type I membrane proteins and localize to the cell membrane, while isoforms 3 and 4 are secreted proteins.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
For Western Blot, is it recommended to use denatured or non-denatured conditions with PILR-α (47-12): sc-100286 antibody?
Asked by: jenni
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.